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Dr. Huaxiao Yang

Assistant Professor

University of North Texas

Department of Biomedical Engineering

(940-369-8959) -

Email: Huaxiao.Yang@unt.edu

Education

  • PhD, Clemson University, 2015
    Major: Bioengineering
  • MSc, Fudan University, 2010
    Major: Macromolecular Science
  • BE, Huazhong University of Science and Technology, 2007
    Major: Chemical Engineering
  • BS, Wuhan University, 2007
    Major: Biological Science

Professional Positions

    Professional

  • Assistant Professor, University of North Texas. University of North Texas. (2020 - Present).
  • Postdoctoral Fellow, Stanford University. Stanford University. (2015 - 2020).
  • Research Assistant, Clemson University. Clemson University. (2010 - 2015).
  • Teaching Assistant, Clemson University. Clemson University. (2013 - 2014).
  • Teaching Assistant, Fudan University. Fudan University. (2008 - 2009).

Professional Memberships

  • Society For Biomaterials. (March 3, 2023 - Present).
  • American Heart Association. (2015 - 2021).
  • Biomedical Engineering Society. (2011 - 2021).

Teaching

Teaching Experience

    University of North Texas

  • BMEN 2900 - Special Problems in Biomedical Engineering, 4 courses.
  • BMEN 3996 - Honors College Mentored Research Experience, 2 courses.
  • BMEN 4320 - Biomedical Microelectromechanical Systems, 15 courses.
  • BMEN 4900 - Special Problems in Biomedical Engineering, 1 course.
  • BMEN 5210 - Biomedical Engineering Laboratory, 28 courses.
  • BMEN 5324 - Applications of Biomedical MEMS, 9 courses.
  • BMEN 5900 - Special Problems in Biomedical Engineering, 8 courses.
  • BMEN 5940 - Biomedical Engineering Seminar, 6 courses.
  • BMEN 5950 - Master's Thesis, 12 courses.
  • BMEN 6910 - Individual Research, 10 courses.
  • BMEN 6940 - Biomedical Engineering Doctoral Seminar, 5 courses.
  • BMEN 6950 - Biomedical Engineering Doctoral Dissertation, 3 courses.

Non-Credit Instruction

  • Guest Lecture, Biomedical Engineering BMEN 1300, (2020).

Directed Student Learning

  • Master's Thesis Committee Chair, Biomedical Engineering. (2023).
  • Dissertation Committee Member, Biomedical Engineering. (2022).
  • Doctoral Advisory Committee Chair, Biomedical Engineering. (2022).
  • Master's Thesis Committee Chair, Biomedical Engineering. (2022).
  • Master's Thesis Committee Chair, Biomedical Engineering. (2022).
  • Master's Thesis Committee Member, Biomedical Engineering. (2022).
  • Supervised Research, Biomedical Engineering. (2022).
  • Dissertation Committee Member, Biomedical Engineering. (2021).
  • Master's Thesis Committee Member, Biomedical Engineering. (2021).
  • Supervised Research, Biomedical Engineering. (2021).
  • Doctoral Advisory Committee Chair, Biomedical Engineering. (2020).
  • Master's Thesis Committee Chair, Biomedical Engineering. (2023 - 2023).
  • Master's Thesis Committee Chair, Biomedical Engineering. (2023 - 2023).
  • Dissertation Committee Member, Biomedical Engineering. (2022 - 2023).
  • Dissertation Committee Member, Biomedical Engineering. (2022 - 2023).
  • Doctoral Advisory Committee Member, Biomedical Engineering. (2022 - 2023).
  • Supervised Research, Honors College. (2022 - 2023).
  • Supervised Research, Honors College. (2022 - 2023).
  • Supervised Research, Biomedical Engineering. (August 2021 - 2023).
  • Supervised Research, Honors College. (2021 - 2022).
  • Supervised Research, Biomedical Engineering. (2020 - 2022).
  • Supervised Research, Biomedical Engineering. (2020 - 2022).
  • Supervised Research, Biomedical Engineering. (2020 - 2022).
  • Supervised Research, Biomedical Engineering. (2020 - 2021).
  • Supervised Research, Biomedical Engineering. (2020 - 2021).

Awards and Honors

  • BMES Hub host and moderator, Biomedical Engineering Society. (2025).
  • NIH Complement-ARIE Challenge Prize Award, NIH. (2024).
  • Diversity Committee of 2024 BMES Annual Meeting, Biomedical Engineering Society. (October 2024).
  • Session Co-Chairs in BMES Annual Meeting 2024, Biomedical Engineering Society. (October 2024).
  • Mentee of AHA BCVS Early Career Mentorship program, American Heart Association. (March 23, 2023).
  • UNT-DEEN Faculty Fellow, University of North Texas. (2022).
  • Session Co-Chairs in BMES Annual Meeting 2023, Biomedical Engineering Society. (October 2023).
  • UNT Washington DC Faculty Fellow, UNT. (January 2021).
  • BioTek Imaging Perspectives 2020, BioTek. (2020).
  • Postdoctoral Fellowship Award, American Heart Association. (2018).
  • Semi-finalist of HOOKEd on Microscopy Contest, Clemson University. (2015).
  • Exxon Mobil Scholarship, Fudan University. (2010).
  • Excellent Students, Fudan UniversityThis field is required. (2007).
  • 1st Class Scholarship, Huazhong University of Science and Technology. (2004).

Research

Published Intellectual Contributions

    Conference Proceeding

  • Jahed, Z., Yang, Y., Yang, H., McGuire, A., Liu, A., Li, X., Cui, B. (2020). Developing Nanoelectrodes into Robust Electrophysiological Tools for Accurate and Parallel Recording of Action Potentials from Single Cells. Biophysical Journal. 118 (3) 28A-28A.
  • Wu, H., Yang, H., Rhee, J., Zhang, J., Lam, C.K., Sallam, K., Chang, A.C., Ma, N., Blau, H., Bers, D., Wu, J. (2018). Modeling of Diastolic Dysfunction in Induced Pluripotent Stem Cell-derived Cardiomyocytes From Hypertrophic Cardiomyopathy Patients. Circulation Research. 123
  • Wu, H., Yang, H., Zhang, J., Lam, C.K., Rhee, J., Seeger, T., Sallam, K., Ma, N., Wu, J. (2017). Restoration of Impaired Diastolic Function in Hypertrophic Cardiomyopathy Induced Pluripotent Stem Cell-derived Cardiomyocytes by Re-balancing the Calcium Homeostasis. Circulation Research. 121
  • Qin, X., Chen, H., Li, K., Yang, H., Wu, H., Zhao, X., Daldrup-Link, H., Wu, J.C. (2017). Tracking Human Pluripotent Stem Cell-Derived Cardiomyocytes in Post-Myocardial Infarction Heart with Photoacoustic Imaging. Circulation Research. 121
  • Wu, H., Yang, H., Seeger, T., Lam, C.K., Zhang, J.Z., Wu, J.C. (2016). Restoration of Impaired Diastolic Function in Induced Pluripotent Stem Cell Derived Cardiomyocytes From Hypertrophic Cardiomyopathy Patients by Re-Balancing the Calcium Homeostasis. Circulation. 134
  • Zhao, M., Chen, H., Liu, Q., Sayed, N., Shao, N., Kim, Y., Yang, H., Chour, T., Ma, H., Tippner-Hedges, R., Mitalipov, S., Snyder, M., Wu, J. (2016). Transcriptomic and Epigenomic Resemblance of Terminally Differentiated Cells Derived From Isogenic Human iPSCs and Nuclear Transfer Derived ESCs. Circulation. 134
  • Zhao, M., Chen, H., Liu, Q., Sayed, N., Shao, N., Kim, Y., Yang, H., Chour, T., Ma, H., Tippner-Hedges, R., Mitalipov, S., Snyder, M., Wu, J. (2016). Transcriptomic and Epigenomic Resemblance of Terminally Differentiated Cells Derived From Isogenic Human iPSCs and Nuclear Transfer Derived ESCs. Circulation. 134
  • Yang, H., Runyan, R.B., Borg, T.K., Markwald, R., Xu, M., Gao, B.Z. (2014). Myocardial Rescue by Mesenchymal Stem Cell via Tunneling Nanotube Formation. Circulation. 130

    • Journal Article

  • Liu, C., Shen, M., Liu, Y., Manhas, A., Zhao, S.R., Zhang, M., Belbachir, N., Ren, L., Zhang, J.Z., Caudal, A., Nishiga, M., Thomas, D., Zhang, A., Yang, H., Zhou, Y., Ameen, M., Sayed, N., Rhee, J., Qi, L.S., Wu, J.C. (2024). CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicity. Other. 31 (12) 1760-1776.e9. Elsevier BV. https://doi.org/10.1016/j.stem.2024.10.007
  • Yang, H., Kumar Reddy Kandula, Arun, Phamornratanakun, T., Huerta Gomez, A., El-Mokahal, M., Ma, Z., Feng, Y. (2024). Abstract We016: Generative Artificial Intelligence for hPSC-derived Cardiac Organoid Florescence Generation. Circulation Research. 135 (Suppl\_1) AWe016--AWe016. Lippincott Williams \& Wilkins Hagerstown, MD.
  • Yang, Y., Valencia, L.A., Lu, C., Nakamoto, M.L., Tsai, C., Liu, C., Yang, H., Zhang, W., Jahed, Z., Lee, W., Santoro, F., Liou, J., Wu, J.C., Cui, B. (2024). Plasma membrane curvature regulates the formation of contacts with the endoplasmic reticulum. Other. 26 (11) 1878-1891. Springer Science and Business Media LLC. https://doi.org/10.1038/s41556-024-01511-x
  • Kandula AKR, Phamornratanakun, T., Gomez, A.H., El-Mokahal, M., Ma, Z., Feng, Y., Yang, H. (2024). Generative AI for Cell Type-Specific Fluorescence Image Generation of hPSC-derived Cardiac Organoid.. Other.
  • Medisetti, G., Compson, Z.G., Fan, H., Yang, H., Feng, Y. (2024). LitAI: Enhancing Multimodal Literature Understanding and Mining with Generative AI.. Other. 2024 471-476.
  • Wen, Y., Yang, H., Hong, Y. (2024). Transcriptomic Approaches to Cardiomyocyte-Biomaterial Interactions: A Review.. ACS Biomaterials Science & Engineering. 10 (7) 4175-4194.
  • Kowalczewski, A., Sun, S., Mai, N.Y., Song, Y., Hoang, P., Liu, X., Yang, H., Ma, Z. (2024). Design optimization of geometrically confined cardiac organoids enabled by machine learning techniques.. Other. 4 (6) 100798.
  • Taylor, A., Xu, J., Rogozinski, N., Fu, H., Molina Cortez, L., McMahan, S., Chang, Y., Pan, Z., Yang, H., Liao, J., Hong, Y. (2024). Reduced Graphene-Oxide-Doped Elastic Biodegradable Polyurethane Fibers for Cardiomyocyte Maturation.. ACS Biomaterials Science & Engineering. 10 (6) 3759-3774.
  • Shi, H., Kowalczewski, A., Vu, D., Liu, X., Salekin, A., Yang, H., Ma, Z. (2024). Organoid intelligence: Integration of organoid technology and artificial intelligence in the new era of in vitro models.. Other. 21
  • Fouladgar, F., Moslabeh, F.G., Kasani, Y.V., Rogozinski, N., Torres, M., Ecker, M.J., Yang, H., Yang, Y., Habibi, N. (2024). Mesenchymal stem cells aligned and stretched in self-assembling peptide hydrogels. Other. 10 (1) e23953. https://www.sciencedirect.com/science/article/pii/S2405844023111613
  • Maramraju, S., Kowalczewski, A., Kaza, A., Liu, X., Singaraju, J.P., Albert, M.V., Ma, Z., Yang, H. (2024). AI-organoid integrated systems for biomedical studies and applications.. Other. 9 (2) e10641.
  • Singaraju, J.P., Kadiresan, A., Bhoi, R.K., Gomez, A.H., Ma, Z., Yang, H. (2023). Organalysis: Multifunctional Image Preprocessing and Analysis Software for Cardiac Organoid Studies.. Other. 29 (12) 572-582.
  • Tu, C., Caudal, A., Liu, Y., Gorgodze, N., Zhang, H., Lam, C.K., Dai, Y., Zhang, A., Wnorowski, A., Wu, M.A., Yang, H., Abilez, O.J., Lyu, X., Narayan, S.M., Mestroni, L., Taylor MRG, Recchia, F.A., Wu, J.C. (2023). Tachycardia-induced metabolic rewiring as a driver of contractile dysfunction.. Other.
  • Liu, C., Shen, M., Tan WLW, Chen, I.Y., Liu, Y., Yu, X., Yang, H., Zhang, A., Liu, Y., Zhao, M.T., Ameen, M., Zhang, M., Gross, E.R., Qi, L.S., Sayed, N., Wu, J.C. (2023). Statins improve endothelial function via suppression of epigenetic-driven EndMT.. Other. 2 (5) 467-485.
  • Rogozinski, N., Yanez, A., Bhoi, R., Lee, M., Yang, H. (2022). Current methods for fabricating 3D cardiac engineered constructs. iScience.
  • Strimaityte, D., Tu, C., Yanez, A., Itzhaki, I., Wu, H., Wu, J.C., Yang, H. (2022). Contractility and Calcium Transient Maturation in the Human iPSC-Derived Cardiac Microfibers.. ACS Applied Materials & Interfaces. 14 (31) 35376-35388.
  • Wang, J., Soto, F., Ma, P., Ahmed, R., Yang, H., Chen, S., Wang, J., Liu, C., Akin, D., Fu, K., Cao, X., Chen, P., Hsu, E.C., Soh, H.T., Stoyanova, T., Wu, J.C., Demirci, U. (2022). Acoustic Fabrication of Living Cardiomyocyte-based Hybrid Biorobots.. ACS Nano. 16 (7) 10219-10230.
  • Jahed, Z., Yang, Y., Tsai, C.T., Foster, E.P., McGuire, A.F., Yang, H., Liu, A., Forro, C., Yan, Z., Jiang, X., Zhao, M.T., Zhang, W., Li , X., Li , T., Pawlosky, A., Wu, J.C., Cui, B. (2022). Nanocrown electrodes for parallel and robust intracellular recording of cardiomyocytes.. Nature Communications. 13 (1) 2253.
  • Gomez, A.H., Joshi, S., Yang, Y., Tune, J.D., Zhao, M., Yang, H. (2021). Bioengineering Systems for Modulating Notch Signaling in Cardiovascular Development, Disease, and Regeneration. Journal of Cardiovascular Development and Disease. 8 (10) 125. MDPI.
  • Gomez, A.H., Joshi, S., Yang, Y., Tune, J.D., Zhao, M.T., Yang, H. (2021). Bioengineering Systems for Modulating Notch Signaling in Cardiovascular Development, Disease, and Regeneration.. Journal of Cardiovascular Development and Disease. 8 (10)
  • Yang, H., Shao, N., Holmström, A., Zhao, X., Chour, T., Chen, H., Itzhaki, I., Wu, H., Ameen, M., Cunningham, N.J., Tu, C., Zhao, M.T., Tarantal, A.F., Abilez, O.J., Wu, J.C. (2021). Transcriptome analysis of non human primate-induced pluripotent stem cell-derived cardiomyocytes in 2D monolayer culture vs. 3D engineered heart tissue.. Other. 117 (9) 2125-2136.
  • Chen, H., Yang, H., Zhang, C., Chen, S., Zhao, X., Zhu, M., Wang, Z., Wang, Y., Wo, H.T., Li , K., Cheng, Z. (2021). Differential Responses of Transplanted Stem Cells to Diseased Environment Unveiled by a Molecular NIR-II Cell Tracker.. Other. 2021 9798580.
  • Joshi, S., Lee, W.H., Chen, P., Serpooshan, V., Yang, H. (2021). Editorial: 3D Cell Culture Systems for Cardiovascular Tissue Engineering: In vitro Modelling and in vivo Regenerative Therapies.. Other. 8 675676.
  • Wilson, K.D., Ameen, M., Guo, H., Abilez, O.J., Tian, L., Mumbach, M.R., Diecke, S., Qin, X., Liu, Y., Yang, H., Ma, N., Gaddam, S., Cunningham, N.J., Gu, M., Neofytou, E., Prado, M., Hildebrandt, T.B., Karakikes, I., Chang, H.Y., Wu, J.C. (2020). Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human Primates. Developmental Cell. 54 (6) 694-+.
  • Lee, S., Yang, H., Chen, C., Venkatraman, S., Darsha, A., Wu, S.M., Wu, J.C., Seeger, T. (2020). Simple Lithography-Free Single Cell Micropatterning using Laser-Cut Stencils. Other. (158)
  • Seeger, T., Shrestha, R., Lam, C.K., Chen, C., McKeithan, W.L., Lau, E., Wnorowski, A., McMullen, G., Greenhaw, M., Lee, J., Oikonomopoulos, A., Lee, S., Yang, H., Mercola, M., Wheeler, M., Ashley, E.A., Yang, F., Karakikes, I., Wu, J.C. (2019). A Premature Termination Codon Mutation in MYBPC3 Causes Hypertrophic Cardiomyopathy via Chronic Activation of Nonsense-Mediated Decay. Circulation. 139 (6) 799-811.
  • Yang, H., Qin, X., Wang, H., Zhao, X., Liu, Y., Wo, H., Liu, C., Nishiga, M., Chen, H., Ge, J., Sayed, N., Abilez, O.J., Ding, D., Heilshorn, S.C., Li, K. (2019). An in Vivo miRNA Delivery System for Restoring Infarcted Myocardium. ACS Nano. 13 (9) 9880-9894.
  • Wu, H., Yang, H., Rhee, J., Zhang, J.Z., Lam, C.K., Sallam, K., Chang, Alex C. Y., Ma, N., Lee, J., Zhang, H., Blau, H.M., Bers, D.M., Wu, J.C. (2019). Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients. Other. 40 (45) 3685-+.
  • Wnorowski, A., Yang, H., Wu, J.C. (2019). Progress, obstacles, and limitations in the use of stem cells in organ-on-a-chip models. Other. 140 3-11.
  • Zhao, X., Chen, H., Xiao, D., Yang, H., Itzhaki, I., Qin, X., Chour, T., Aguirre, A., Lehmann, K., Kim, Y., Shukla, P., Holmstrom, A., Zhang, J.Z., Yan Zhuge, Ndoye, B.C., Zhao, M., Neofytou, E., Zimmermann, W., Jain, M., Wu, J.C. (2018). Comparison of Non-human Primate versus Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Treatment of Myocardial Infarction. Other. 10 (2) 422-435.
  • Abilez, O.J., Tzatzalos, E., Yang, H., Zhao, M., Jung, G., Zollner, A.M., Tiburcy, M., Riegler, J., Matsa, E., Shukla, P., Yan Zhuge, Chour, T., Chen, V.C., Burridge, P.W., Karakikes, I., Kuhl, E., Bernstein, D., Couture, L.A., Gold, J.D., Zimmermann, W.H., Wu, J.C. (2018). Passive Stretch Induces Structural and Functional Maturation of Engineered Heart Muscle as Predicted by Computational Modeling. Other. 36 (2) 265-277.
  • Qin, X., Chen, H., Yang, H., Wu, H., Zhao, X., Wang, H., Chour, T., Neofytou, E., Ding, D., Daldrup-Link, H., Heilshorn, S.C., Li, K., Wu, J.C. (2018). Photoacoustic Imaging of Embryonic Stem Cell-Derived Cardiomyocytes in Living Hearts with Ultrasensitive Semiconducting Polymer Nanoparticles. Advanced Functional Materials. 28 (1)
  • Zhao, M., Chen, H., Liu, Q., Shao, N., Sayed, N., Wo, H., Zhang, J.Z., Ong, S., Liu, C., Kim, Y., Yang, H., Chour, T., Ma, H., Gutierrez, N.M., Karakikes, I., Mitalipov, S., Snyder, M.P., Wu, J.C. (2017). Molecular and functional resemblance of differentiated cells derived from isogenic human iPSCs and SCNT-derived ESCs. Proceedings of the National Academy of Sciences of the United States of America. 114 (52) E11111-E11120.
  • Yang, H., Borg, T.K., Ma, Z., Xu, M., Wetzel, G., Saraf, L.V., Markwald, R., Runyan, R.B., Gao, B.Z. (2016). Biochip-based study of unidirectional mitochondrial transfer from stem cells to myocytes via tunneling nanotubes. Biofabrication. 8 (1)
  • Yang, H., Schmidt, L.P., Wang, Z., Yang, X., Shao, Y., Borg, T.K., Markwald, R., Runyan, R., Gao, B.Z. (2016). Dynamic Myofibrillar Remodeling in Live Cardiomyocytes under Static Stretch. Scientific Reports. 6
  • Yang, H., Borg, T.K., Liu, H., Gao, B.Z. (2015). Interactive relationship between basement-membrane development and sarcomerogenesis in single cardiomyocytes. Other. 330 (1) 222-232.
  • Liu, H., Chen, R., Yang, H., Qin, W., Borg, T.K., Dean, D., Xu, M., Gao, B.Z. (2014). Enzyme-etching technique to fabricate micropatterns of aligned collagen fibrils. Other. 36 (6) 1245-1252.
  • Yang, H., Borg, T.K., Schmidt, L.P., Gao, B.Z. (2014). Laser cell-micropatterned pair of cardiomyocytes: the relationship between basement membrane development and gap junction maturation. Biofabrication. 6 (4)
  • Yang, H., Borg, T.K., Wang, Z., Ma, Z., Gao, B.Z. (2014). Role of the Basement Membrane in Regulation of Cardiac Electrical Properties. Annals of Biomedical Engineering. 42 (6) 1148-1157.
  • Ma, Z., Liu, Q., Yang, H., Runyan, R.B., Eisenberg, C.A., Xu, M., Borg, T.K., Markwald, R., Wang, Y., Gao, B.Z. (2013). Laser patterning for the study of MSC cardiogenic differentiation at the single-cell level. Other. 2
  • Ma, Z., Yang, H., Liu, H., Xu, M., Runyan, R.B., Eisenberg, C.A., Markwald, R.R., Borg, T.K., Gao, B.Z. (2013). Mesenchymal Stem Cell-Cardiomyocyte Interactions under Defined Contact Modes on Laser-Patterned Biochips. PLOS One. 8 (2)
  • Ma, Z., Liu, Q., Liu, H., Yang, H., Yun, J.X., Xu, M., Eisenberg, C.A., Borg, T.K., Markwald, R., Gao, B.Z. (2012). Cardiogenic Regulation of Stem-Cell Electrical Properties in a Laser-Patterned Biochip. Other. 5 (3) 327-336.
  • Ma, Z., Liu, Q., Liu, H., Yang, H., Yun, J.X., Eisenberg, C., Borg, T.K., Xu, M., Gao, B.Z. (2012). Laser-patterned stem-cell bridges in a cardiac muscle model for on-chip electrical conductivity analyses. Other. 12 (3) 566-573.
  • Yang, H., Ma, Z. (2012). Microsystem for Stem Cell-Based Cardiovascular Research. Other. 2 (4) 305-315.
  • Sun Min, Yang Huaxiao, Zhou Ping, Pan Luanfeng, Liu Shui. (2010). BIOCOMPATIBILITY OF PHBHHx AND SILK FIBROIN-MODIFIED PHBHHx SCAFFOLDS WITH HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS. Other. (12) 1430-1436.
  • Yang, H., Sun, M., Zhou, P. (2009). Investigation of water diffusion in poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) by generalized two-dimensional correlation ATR-FTIR spectroscopy. Polymer. 50 (6) 1533-1540.

Presentations Given

    Invited Talk

  • Yang, H. (Author & Presenter), iCANX Youth Talks, Modeling Cardiovascular Development and Disease with Human Pluripotent Stem Cells in 2D and 3D Models, iCANX, Virtual, China. (2023).
  • Yang, H. (Author & Presenter), Research Advancements for Enabling Precision Medicine in Cardiovascular Disease, Modeling Cardiovascular Development and Disease with Human Pluripotent Stem Cells in 2D and 3D Models, Global Talents in Science, Virtual, United States of America. (2023).
  • Yang, H. (Author & Presenter), UNT Honors College, Studying Heart Development and Disease by Using Engineering Tools, UNT Honors College, UNT Honors College, United States of America. (2023).
  • Yang, H. (Author & Presenter), Department of Chemistry Seminar, 1. Modeling Cardiovascular Development and Disease with Human Pluripotent Stem Cells (hPSC) and Tissue Engineering, the University of Texas at Dallas, the University of Texas at Dallas, United States of America. (2022).
  • Yang, H. (Author & Presenter), ASMB Fibroblast Workshop 2022, 2. Fibroblasts in Cardiac Engineered Constructs for Regenerative Medicine, American Society for Matrix Biology, University of Virgina, United States of America. (2022).
  • Yang, H. (Author & Presenter), 2nd Edition Bioelectronics, Biosensors and Biochips C3B-20-II Virtual Meeting, Engineered heart tissue as a biochip for modeling cardiomyopathies, United States of America. (2020 - 2020).
  • Yang, H. (Author & Presenter), Bioelectronics, Biosensors and Biochips C3B-20 Virtual Meeting, Micropatterned human pluripotent stem cell-derived biochip for cardiac maturation and disease modeling, United States of America. (2020 - 2020).
  • Yang, H. (Author & Presenter), Michigan Tech University, Multiscale Engineering for Cardiovascular Regenerative Medicine and Disease modeling, United States of America. (2020 - 2020).
  • Yang, H. (Author & Presenter), University of North Texas, Multiscale Engineering for Cardiovascular Regenerative Medicine and Disease modeling, United States of America. (2020 - 2020).

    • Poster

  • Yang, H. (Author), Second workshop of imaging and data science, Generative AI for Cardiac Organoid Florescence Generation, University of Texas at Dallas, University of Texas at Dallas, United States of America. (2023).
  • Yang, H. (Author), Society For Biomaterials 2023 Annual Meeting, Micropatterned hiPSC-CMs for disease modeling of hypertrophic cardiomyopathies, Society For Biomaterials, San Diego, CA, United States of America. (2023).
  • Yang, H. (Author), BMES annual meeting, T-tubule Formation and Calcium Transient Maturation on Human iPSC-derived Cardiac Microfibers, BMES, San Antonio, TX, United States of America. (2022).
  • Gomez, A. (Author & Presenter), Kang, S. (Author), El-Mokahal, M. (Author), Lee, M.D. (Author), Yang, H. (Author), BMES Annual Meeting 2024, Enhanced vascularization in hPSC-derived cardiac organoids by dynamic culture, Baltimore, MD, United States of America. (2024 - 2024).
  • Gomez, A. (Author & Presenter), Kang, S. (Author), Bhoi, R. (Author), Seddoh, P. (Author), Lee, M.D. (Author), Yang, H. (Author), BMES Annual Meeting 2022, Engineering cardiac organoid vascularization via fluid shear stress and vascular-promoting growth factors, San Antonio, TX, USA, United States of America. (2022 - 2022).

Contracts, Grants, Sponsored Research

    Contract

  • Yang, H. (Principal), "LOI-HFpEF in a Dish: Establishing a Human in vitro Model," sponsored by AHA, National, Funded. (2024 - 2027).

    • Fellowship

  • Yang, H., "Interrogating the Cardiovascular Toxicity of Volatile Organic Compounds from E-Cigarettes in hiPSC-derived Vascularized Cardiac Organoids," sponsored by American Heart Association (AHA), National, $155716 Funded. (2018 - 2020).
  • Yang, H., "Interrogating the Cardiovascular Toxicity of Volatile Organic Compounds from E-Cigarettes in hiPSC-derived Vascularized Cardiac Organoids," sponsored by American Heart Association (AHA), National, Funded. (2018 - 2020).

    • Grant - Research

  • Feng, Y. (Other), Yang, H. (Principal), "Assessing Tyrosine Kinase Inhibitors-induced Cardiotoxicity with an Organoid-AI System," sponsored by NIH, Federal, $547020 Funded. (2024).
  • Yang, H. (Principal), "NIH R56 Bridge Funding," sponsored by NIH, Federal, $547020 Funded. (2024 - 2025).
  • Yang, H. (Principal), "NOTCH signaling on the underdeveloped cardiac vascularization of hypoplastic left heart syndrome in the hiPSC-derived vascularized cardiac organoids," sponsored by NIH, Federal, $444874 Funded. (2022 - 2025).
  • Yang, H. (Principal), "Prototyping the Human Cardiac Fibrosis by Interfacing the 3D Bioprinting and Clinical Diagnosis for Early Detection of Cardiac Arrhythmogenicity," sponsored by Harry Moss Heart/BOA Trust, Private, $75000 Funded. (2023 - 2024).
  • Yang, H., Tune, J., Albert, M., "Clinical trial in a dish for studying antihypertensive drug induced cardiovascular malformation and dysfunction in gestational hypertension," sponsored by University of North Texas, University of North Texas, $7800 Funded. (2021 - 2022).

Copyrights, Patents

    Patent

  • Yang, H., Singaraju, J.P., Kadiresan, A., Organalysis: a graphical user interface-based multifunctional image preprocessing and analysis software for cardiac organoid studies, 63/514,786. Provisional, Date submitted to the University: 2023. Date of Patent Application: 2023. .
  • Yang, H., Feng, Y., Kandula, A.K., Generative AI for Cardiac Organoid Image Colorization, 63/618,181. Provisional, Date submitted to the University: 2023. Date of Patent Application: 2023. .
  • Yang, H., CREATION OF VASCULARIZED BIOLOGICAL STRUCTURES, S22-080. Regular, Date submitted to the University: February 28, 2022. .

Service

University Service

  • Committee Member, IBC. (2021 - Present).
  • Committee Member, UG Committee. (2021 - Present).
  • Committee Member, BMEN Scholarship Committee. (2020 - 2022).

Public Service

  • Grant Proposal Reviewer, External, 2023 AHA Second Century Early Faculty Independence Award (SCEFIA) Committee. Virtual, Virtual. (2023 - Present).
  • Grant Proposal Reviewer, External, AHA - Transformational Program Award - Bioengineering group. Virtual, Virtual. (2023 - Present).
  • Workshop Organizer, BEI-2023. Boston, (2023 - Present).
  • Session Chair, Biomedical Engineering Society. Seattle, Washington. (2023 - Present).
  • Other (Poster Judge), Goldwater Symposium Poster Competition. Virtual, (2023 - Present).
  • Committee Member, NIH - ZRG1-CDD-Q study section. Virgina. (2023 - Present).
  • Grant Proposal Reviewer, External, AHA pre-/post- doctoral Fellowship. Denton, TX. (2022 - Present).
  • Grant Proposal Reviewer, External, Team Science of Health Science Center-UNTHSC. Denton, TX. (2022 - Present).
  • Grant Proposal Reviewer, External, NSF GRFP. DENTON, TX. (2021 - Present).
  • Grant Proposal Reviewer, External, AHA pre-/post- doctoral Fellowship. Stanford, CA. (2019 - Present).

Professional Service

  • Committee Member, AHA IPA – Basic Science Committee. denton, tx. (2025 - Present).
  • Reviewer, Journal Article, Advanced Functional Materials. DENTON, TX. (2024 - Present).
  • Reviewer, Journal Article, Advanced Healthcare Materials. DENTON, tx. (2024 - Present).
  • Committee Member, AHA pre-/post- Doctoral Fellowship Committee. denton, tx. (2024 - Present).
  • Reviewer, Journal Article, Biomaterials. Denton, tx. (2024 - Present).
  • Reviewer, Journal Article, Computation in Biology and Medicine. denton, tx. (2024 - Present).
  • Reviewer, Journal Article, Ecotoxicology and Environmental Safety. denton, tx. (2024 - Present).
  • Reviewer, Journal Article, Material Today Bio. denton, tx. (2024 - Present).
  • Reviewer, Grant Proposal, NIH Special Emphasis Panel/Scientific Review Group MTI. Bethesda, MD. (2024 - Present).
  • Reviewer, Grant Proposal, NSF BioFoundries. denton, tx. (2024 - Present).
  • Reviewer, Conference Paper, 2023 BMES. (2023 - Present).
  • Reviewer, Journal Article, Advanced Biology. (2023 - Present).
  • Committee Member, AHA Second Century Early Faculty Independence Award (SCEFIA) Committee. denton, tx. (2023 - Present).
  • Committee Member, AHA TPA - Bioengineering Committee. denton, tx. (2023 - Present).
  • Reviewer, Journal Article, Biofabrications. (2023 - Present).
  • Reviewer, Grant Proposal, NIH ZRG1-CDD-Q study section. Charlottesville, virgina. (2023 - Present).
  • Reviewer, Conference Paper, Society for Biomaterials. Denton, (2023 - Present).
  • Reviewer, Conference Paper, TERMIS-AM Annual Conference and Exhibition. (2023 - Present).
  • Reviewer, Conference Paper, National Diversity in STEM Conference, SACNACS. Denton, TX. (December 2022 - Present).
  • Reviewer, Conference Paper, Society for Biomaterials. Denton, TX. (December 2022 - Present).
  • Reviewer, Conference Paper, TERMIS-AM Annual Conference. Denton, TX. (December 2022 - Present).
  • Reviewer, Journal Article, Biomechanics and Modeling in Mechanobiology. DENTON, TX. (2022 - Present).
  • Reviewer, Journal Article, Biomolecules. DENTON, TX. (2022 - Present).
  • Reviewer, Journal Article, Engineered Regeneration. DENTON, TX. (2022 - Present).
  • Reviewer, Conference Paper, Society for Biomaterials. Denton, TX. (December 2021 - Present).
  • Reviewer, Conference Paper, 2021 National Diversity in STEM Conference, SACNAC. Denton, TX. (2021 - Present).
  • Reviewer, Journal Article, 3D Printing and Additive Manufacturing. DENTON, TX. (2021 - Present).
  • Reviewer, Journal Article, ACS biomaterials and engineering. DENTON, TX. (2021 - Present).
  • Editor, Journal Editor, Frontiers in Bioengineering and Biotechnology. DENTON, TX. (2021 - Present).
  • Reviewer, Journal Article, iScience. DENTON, TX. (2021 - Present).
  • Reviewer, Journal Article, Life Sciences. DENTON, TX. (2021 - Present).
  • Reviewer, Journal Article, MRS communications. DENTON, TX. (2021 - Present).
  • Reviewer, Journal Article, Theranostics. DENTON, TX. (2021 - Present).
  • Reviewer, Journal Article, Advanced Drug Delivery Reviews. DENTON, TX. (2020 - Present).
  • Reviewer, Journal Article, Biofabrication. DENTON, TX. (2020 - Present).
  • Reviewer, Journal Article, Current Opinion in Physiology. DENTON, TX. (2020 - Present).
  • Reviewer, Journal Article, Journal of Cellular Physiology. DENTON, TX. (2019 - Present).
  • Editor, Guest Editor, Cells. DENTON, TX. (2021 - 2022).
  • Editor, Guest Editor, Journal of Visualized Experiments. DENTON, TX. (2021 - 2022).
  • Editor, Guest Editor, Frontiers in Cardiovascular Medicine. Denton, TX. (2020 - 2020).