Rohan Balakrishnan
Assistant Professor
University of North Texas
Department of Biological Sciences
Email: Rohan.balakrishnan@unt.edu
Education
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PhD, Ohio State University, 2015
Major: Biochemistry
Dissertation: Role of the Conserved GT Pase LepA in Escherichia Coli
Teaching
Teaching Experience
- BIOL 4801 - Microbial Genetics, 1 course.
University of North Texas
Research
Published Intellectual Contributions
- Fleming, I.M., Paris, Z., Gaston, K.W., Balakrishnan, R., Fredrick, K., Rubio, M.A., Alfonzo, J.D. A tRNA methyltransferase paralog is important for ribosome stability and cell division in Trypanosoma brucei. Scientific Reports. 6 (1) Springer Science and Business Media LLC. http://dx.doi.org/10.1038/srep21438
- Guessous, G., Patsalo, V., Balakrishnan, R., Çağlar, T., Williamson, J.R., Hwa, T. Inherited chitinases enable sustained growth and rapid dispersal of bacteria from chitin particles. Nature Microbiology. 8 (9) 1695-1705. Springer Science and Business Media LLC. http://dx.doi.org/10.1038/s41564-023-01444-5
- Dai, X., Zhu, M., Warren, M., Balakrishnan, R., Patsalo, V., Okano, H., Williamson, J.R., Fredrick, K., Wang, Y., Hwa, T. Reduction of translating ribosomes enables Escherichia coli to maintain elongation rates during slow growth. Nature Microbiology. 2 (2) Springer Science and Business Media LLC. http://dx.doi.org/10.1038/nmicrobiol.2016.231
- Balakrishnan, R., Mori, M., Segota, I., Zhang, Z., Aebersold, R., Ludwig, C., Hwa, T. (2022). Principles of gene regulation quantitatively connect DNA to RNA and proteins in bacteria. Science. 378 (6624) American Association for the Advancement of Science (AAAS). http://dx.doi.org/10.1126/science.abk2066
- Balakrishnan, R., de Silva, R.T., Hwa, T., Cremer, J. (2021). Suboptimal resource allocation in changing environments constrains response and growth in bacteria. Other. 17 (12) Springer Science and Business Media LLC. http://dx.doi.org/10.15252/msb.202110597
- Dai, X., Zhu, M., Warren, M., Balakrishnan, R., Okano, H., Williamson, J.R., Fredrick, K., Hwa, T., Lee, S.Y. (2018). Slowdown of Translational Elongation in Escherichia coli under Hyperosmotic Stress. mBio. 9 (1) American Society for Microbiology. http://dx.doi.org/10.1128/mbio.02375-17
- Gibbs, M.R., Moon, K., Chen, M., Balakrishnan, R., Foster, L.J., Fredrick, K. (2017). Conserved GTPase LepA (Elongation Factor 4) functions in biogenesis of the 30S subunit of the 70S ribosome. Proceedings of the National Academy of Sciences. 114 (5) 980-985. Proceedings of the National Academy of Sciences. http://dx.doi.org/10.1073/pnas.1613665114
- Balakrishnan, R., Oman, K., Shoji, S., Bundschuh, R., Fredrick, K. (2014). The conserved GTPase LepA contributes mainly to translation initiation in Escherichia coli. Other. 42 (21) 13370-13383. Oxford University Press (OUP). http://dx.doi.org/10.1093/nar/gku1098
- Wu, C., Balakrishnan, R., Braniff, N., Mori, M., Manzanarez, G., Zhang, Z., Hwa, T. Cellular perception of growth rate and the mechanistic origin of bacterial growth law. Cold Spring Harbor Laboratory. http://dx.doi.org/10.1101/2021.10.16.464649