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Yanxiao Han

Assistant Professor

University of North Texas

Department of Biological Sciences

Email: Yanxiao.Han@unt.edu

Professional Positions

    Academic - Post-Secondary

  • Doctor of Philosophy, University of Illinois at Chicago. University of Illinois at Chicago. (2015 - 2021).

    • Professional

  • Postdoc, University of California, Davis. University of California, Davis. (2021 - 2025).

Professional Memberships

  • Frontiers of Chemical Biology. (January 1, 2022 - December 31, 2028).
  • Biophysical Society. (January 1, 2021 - December 31, 2028).
  • American Heart Association. (January 1, 2024 - March 31, 2028).
  • Child and Family Care Administrative Advisory Committee. (January 1, 2023 - May 31, 2025).
  • Association of Women in Science. (January 1, 2022 - May 31, 2025).

Development Activities

  • Workshop, Developing Effective Specific Aims and Concept Papers, University of North Texas. Denton,Taxes,United States of America. (December 2, 2025 - December 2, 2025).

Teaching

Teaching Experience

    University of North Texas

  • BIOL 4005 - Contemporary Topics in Biology, 1 course.
  • BIOL 5005 - TOPICS IN BIOLOGY, 1 course.

Teaching at Other Institutions

  • University of California Davis, Computational Biomedical Internship, Summer 2024.

Awards and Honors

  • Career Development Award, American Heart Association. (April 1, 2025).
  • Postdoctoral Fellowship, American Heart Association. (April 1, 2024).
  • D. E. Shaw Research Postdoctoral Fellowship, D. E. Shaw Research. (February 2025).

Research

Published Intellectual Contributions

    Abstracts and Proceedings

  • Han, Y., Rouen, K., Xiang, Y.K., Yarov-Yarovoy, V., Clancy, C.E., Ahn, S., Vorobyov, I.V. (2025). BPS2025-In silico pipeline to assess the dynamic interplay between $\beta$-adrenergic receptors, its agonists, and different G proteins. Biophysical Journal. 124 (3) 234a. Elsevier.
  • Ngo, K., Mateos, D.L., Han, Y., Rouen, K.C., Ahn, S., Wulff, H., Clancy, C.E., Yarov-Yarovoy, V., Vorobyov, I. (2024). From Tarantula Venom to Therapeutics: Unveiling Protoxin-2’s Binding to Pain-Sensing Human NaV1. 7 Channels. Other. 67.

    • Book Chapter

  • DeMarco, K.R., Dawson, J.R., Rouen, K.C., Ngo, K., Han, Y., Yang, P., Bekker, S., Ngo, Van A, Noskov, S.Y., Yarov-Yarovoy, V., others. (2025). Atomistic Modeling Toward Predictive Cardiotoxicity. Molecular and Computational Modeling of Cardiac Function. 77--118. Springer.
  • Bekker, S., Han, Y., Vorobyov, I. (2025). Introduction to Atomistic Modeling and Simulation of Biomolecular Systems. Molecular and Computational Modeling of Cardiac Function. 1--75. Springer.

    • Journal Article

  • Rouen, K.C., Narang, K., Han, Y., Wang, D., Jang, E., Brunkow, S., Yarov-Yarovoy, V., MacKerell, Jr, A.D., Vorobyov, I. (2025). Arrhythmia risk predictions from molecular simulations of cardiac ion channel-drug interactions. Biophysical Journal. 2025--09. Cell Press.
  • Han, Y., Rouen, K.C., Yarov-Yarovoy, V., Clancy, C.E., Xiang, Y.K., Vorobyov, I., Ahn, S. (2025). Ligand Dissociation Pathways from Membrane Receptors Revealed by Weighted Ensemble Simulations. The Journal of Physical Chemistry B. ACS Publications.
  • Han, Y., Dawson, J.R., DeMarco, K.R., Rouen, K.C., Ngo, K., Bekker, S., Yarov-Yarovoy, V., Clancy, C.E., Xiang, Y.K., Ahn, S., others. (2025). Molecular simulations reveal intricate coupling between agonist-bound $\beta$-Adrenergic Receptors and G Protein. iScience. 111741. Elsevier.
  • Yang, P., Rose, A., DeMarco, K.R., Dawson, J.R., Han, Y., Jeng, M., Harvey, R.D., Santana, L.F., Ripplinger, C.M., Vorobyov, I., others. (2023). A multiscale predictive digital twin for neurocardiac modulation. Journal of Physiology. 601 (17) 3789--3812.
  • Han, Y., Dawson, J.R., DeMarco, K.R., Rouen, K.C., Bekker, S., Yarov-Yarovoy, V., Clancy, C.E., Xiang, Y.K., Vorobyov, I. (2023). Elucidation of a dynamic interplay between a beta-2 adrenergic receptor, its agonist, and stimulatory G protein. Proceedings of the National Academy of Sciences. 120 (10) e2215916120. National Acad Sciences.
  • Kr\'al, Petr, Chan, H., Vukovi\'c, Lela, Raj, S., Sen, S., Han, Y., Sawczyk, M. (2023). Simulation Methods for Self-Assembling Nanoparticles. Other. 101225. Elsevier.

    • Manuscript

  • Dawson, J.R., DeMarco, K.R., Han, Y., Bekker, S., Clancy, C.E., Yarov-Yarovoy, V., Vorobyov, I. (2023). Modeling stereospecific drug interactions with beta-adrenergic receptors. Other. 2023--10. Cold Spring Harbor Laboratory.

Media Contributions

    Internet

  • "“Invisible” Protein Movements Revealed by Anton 2 Simulations," PSC. (June 8, 2023).

Contracts, Grants, Sponsored Research

    Grant - Research

  • Han, Y. (Principal), "Pharmacological Modulation of Estrogen and Adrenergic Receptors," sponsored by American Heart Association, National, $231000 Funded. (2025 - 2028).
  • Han, Y. (Principal), "Cooperation of Estrogen and Adrenergic Receptors in Cardiovascular Function: Mechanism and Impact," sponsored by American Heart Association, National, $151564 Funded. (2024 - 2025).

Service

Professional Service

  • Editor, Associate Editor, Frontiers in Chemical Biology. (October 1, 2025 - March 1, 2028).