Faculty Profile

Adam Yang

Title
Assistant Professor
Department
Biomedical Engineering
College
College of Engineering

    

Education

DPhil, Clemson University, 2015.
Major: Bioengineering
MSc, Fudan University, 2010.
Major: Macromolecular Science
BE, Huazhong University of Science and Technology, 2007.
Major: Chemical Engineering
BS, Wuhan University, 2007.
Major: Biological Science

Current Scheduled Teaching*

BMEN 5950.005, Master's Thesis, Summer 2021
BMEN 2900.005, Special Problems in Biomedical Engineering, Summer 2021
BMEN 5900.005, Special Problems in Biomedical Engineering, Summer 2021

* Texas Education Code 51.974 (HB 2504) requires each institution of higher education to make available to the public, a syllabus for undergraduate lecture courses offered for credit by the institution.

Previous Scheduled Teaching*

BMEN 5324.001, Applications of Biomedical MEMS, Spring 2021 Syllabus SPOT
BMEN 5324.601, Applications of Biomedical MEMS, Spring 2021 Syllabus SPOT
BMEN 4320.001, Biomedical Microelectromechanical Systems, Spring 2021 Syllabus SPOT
BMEN 5950.008, Master's Thesis, Spring 2021
BMEN 2900.008, Special Problems in Biomedical Engineering, Spring 2021
BMEN 5900.008, Special Problems in Biomedical Engineering, Spring 2021
BMEN 5210.001, Biomedical Engineering Laboratory, Fall 2020 Syllabus SPOT
BMEN 5940.001, Biomedical Engineering Seminar, Fall 2020 Syllabus SPOT

* Texas Education Code 51.974 (HB 2504) requires each institution of higher education to make available to the public, a syllabus for undergraduate lecture courses offered for credit by the institution.

Published Publications

Published Intellectual Contributions

Conference Proceeding
Jahed, Z., Yang, Y., Yang, H., McGuire, A., Liu, A., Li, X., Cui, B. (2020). Developing Nanoelectrodes into Robust Electrophysiological Tools for Accurate and Parallel Recording of Action Potentials from Single Cells. Biophysical Journal. 118(3), 28A-28A.
Wu, H., Yang, H., Rhee, J., Zhang, J., Lam, C. K., Sallam, K., Chang, A. C., Ma, N., Blau, H., Bers, D., Wu, J. (2018). Modeling of Diastolic Dysfunction in Induced Pluripotent Stem Cell-derived Cardiomyocytes From Hypertrophic Cardiomyopathy Patients. Circulation Research. 123, .
Wu, H., Yang, H., Zhang, J., Lam, C. K., Rhee, J., Seeger, T., Sallam, K., Ma, N., Wu, J. (2017). Restoration of Impaired Diastolic Function in Hypertrophic Cardiomyopathy Induced Pluripotent Stem Cell-derived Cardiomyocytes by Re-balancing the Calcium Homeostasis. Circulation Research. 121, .
Qin, X., Chen, H., Li, K., Yang, H., Wu, H., Zhao, X., Daldrup-Link, H., Wu, J. C. (2017). Tracking Human Pluripotent Stem Cell-Derived Cardiomyocytes in Post-Myocardial Infarction Heart with Photoacoustic Imaging. Circulation Research. 121, .
Wu, H., Yang, H., Seeger, T., Lam, C. K., Zhang, J. Z., Wu, J. C. (2016). Restoration of Impaired Diastolic Function in Induced Pluripotent Stem Cell Derived Cardiomyocytes From Hypertrophic Cardiomyopathy Patients by Re-Balancing the Calcium Homeostasis. Circulation. 134, .
Zhao, M., Chen, H., Liu, Q., Sayed, N., Shao, N., Kim, Y., Yang, H., Chour, T., Ma, H., Tippner-Hedges, R., Mitalipov, S., Snyder, M., Wu, J. (2016). Transcriptomic and Epigenomic Resemblance of Terminally Differentiated Cells Derived From Isogenic Human iPSCs and Nuclear Transfer Derived ESCs. Circulation. 134, .
Zhao, M., Chen, H., Liu, Q., Sayed, N., Shao, N., Kim, Y., Yang, H., Chour, T., Ma, H., Tippner-Hedges, R., Mitalipov, S., Snyder, M., Wu, J. (2016). Transcriptomic and Epigenomic Resemblance of Terminally Differentiated Cells Derived From Isogenic Human iPSCs and Nuclear Transfer Derived ESCs. Circulation. 134, .
Yang, H., Runyan, R. B., Borg, T. K., Markwald, R., Xu, M., Gao, B. Z. (2014). Myocardial Rescue by Mesenchymal Stem Cell via Tunneling Nanotube Formation. Circulation. 130, .
Journal Article
Wilson, K. D., Ameen, M., Guo, H., Abilez, O. J., Tian, L., Mumbach, M. R., Diecke, S., Qin, X., Liu, Y., Yang, H., Ma, N., Gaddam, S., Cunningham, N. J., Gu, M., Neofytou, E., Prado, M., Hildebrandt, T. B., Karakikes, I., Chang, H. Y., Wu, J. C. (2020). Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human Primates. Developmental Cell. 54(6), 694-+.
Lee, S., Yang, H., Chen, C., Venkatraman, S., Darsha, A., Wu, S. M., Wu, J. C., Seeger, T. (2020). Simple Lithography-Free Single Cell Micropatterning using Laser-Cut Stencils. Other. (158), .
Seeger, T., Shrestha, R., Lam, C. K., Chen, C., McKeithan, W. L., Lau, E., Wnorowski, A., McMullen, G., Greenhaw, M., Lee, J., Oikonomopoulos, A., Lee, S., Yang, H., Mercola, M., Wheeler, M., Ashley, E. A., Yang, F., Karakikes, I., Wu, J. C. (2019). A Premature Termination Codon Mutation in MYBPC3 Causes Hypertrophic Cardiomyopathy via Chronic Activation of Nonsense-Mediated Decay. Circulation. 139(6), 799-811.
Yang, H., Qin, X., Wang, H., Zhao, X., Liu, Y., Wo, H., Liu, C., Nishiga, M., Chen, H., Ge, J., Sayed, N., Abilez, O. J., Ding, D., Heilshorn, S. C., Li, K. (2019). An in Vivo miRNA Delivery System for Restoring Infarcted Myocardium. ACS Nano. 13(9), 9880-9894.
Wu, H., Yang, H., Rhee, J., Zhang, J. Z., Lam, C. K., Sallam, K., Chang, Alex C. Y.,, Ma, N., Lee, J., Zhang, H., Blau, H. M., Bers, D. M., Wu, J. C. (2019). Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients. Other. 40(45), 3685-+.
Zhao, X., Chen, H., Xiao, D., Yang, H., Itzhaki, I., Qin, X., Chour, T., Aguirre, A., Lehmann, K., Kim, Y., Shukla, P., Holmstrom, A., Zhang, J. Z., Yan Zhuge,, Ndoye, B. C., Zhao, M., Neofytou, E., Zimmermann, W., Jain, M., Wu, J. C. (2018). Comparison of Non-human Primate versus Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Treatment of Myocardial Infarction. Other. 10(2), 422-435.
Abilez, O. J., Tzatzalos, E., Yang, H., Zhao, M., Jung, G., Zollner, A. M., Tiburcy, M., Riegler, J., Matsa, E., Shukla, P., Yan Zhuge,, Chour, T., Chen, V. C., Burridge, P. W., Karakikes, I., Kuhl, E., Bernstein, D., Couture, L. A., Gold, J. D., Zimmermann, W. H., Wu, J. C. (2018). Passive Stretch Induces Structural and Functional Maturation of Engineered Heart Muscle as Predicted by Computational Modeling. Other. 36(2), 265-277.
Qin, X., Chen, H., Yang, H., Wu, H., Zhao, X., Wang, H., Chour, T., Neofytou, E., Ding, D., Daldrup-Link, H., Heilshorn, S. C., Li, K., Wu, J. C. (2018). Photoacoustic Imaging of Embryonic Stem Cell-Derived Cardiomyocytes in Living Hearts with Ultrasensitive Semiconducting Polymer Nanoparticles. Advanced Functional Materials. 28(1), .
Zhao, M., Chen, H., Liu, Q., Shao, N., Sayed, N., Wo, H., Zhang, J. Z., Ong, S., Liu, C., Kim, Y., Yang, H., Chour, T., Ma, H., Gutierrez, N. M., Karakikes, I., Mitalipov, S., Snyder, M. P., Wu, J. C. (2017). Molecular and functional resemblance of differentiated cells derived from isogenic human iPSCs and SCNT-derived ESCs. Proceedings of the National Academy of Sciences of the United States of America. 114(52), E11111-E11120.
Yang, H., Borg, T. K., Ma, Z., Xu, M., Wetzel, G., Saraf, L. V., Markwald, R., Runyan, R. B., Gao, B. Z. (2016). Biochip-based study of unidirectional mitochondrial transfer from stem cells to myocytes via tunneling nanotubes. Biofabrication. 8(1), .
Yang, H., Schmidt, L. P., Wang, Z., Yang, X., Shao, Y., Borg, T. K., Markwald, R., Runyan, R., Gao, B. Z. (2016). Dynamic Myofibrillar Remodeling in Live Cardiomyocytes under Static Stretch. Scientific Reports. 6, .
Yang, H., Borg, T. K., Liu, H., Gao, B. Z. (2015). Interactive relationship between basement-membrane development and sarcomerogenesis in single cardiomyocytes. Other. 330(1), 222-232.
Liu, H., Chen, R., Yang, H., Qin, W., Borg, T. K., Dean, D., Xu, M., Gao, B. Z. (2014). Enzyme-etching technique to fabricate micropatterns of aligned collagen fibrils. Other. 36(6), 1245-1252.
Yang, H., Borg, T. K., Schmidt, L. P., Gao, B. Z. (2014). Laser cell-micropatterned pair of cardiomyocytes: the relationship between basement membrane development and gap junction maturation. Biofabrication. 6(4), .
Yang, H., Borg, T. K., Wang, Z., Ma, Z., Gao, B. Z. (2014). Role of the Basement Membrane in Regulation of Cardiac Electrical Properties. Annals of Biomedical Engineering. 42(6), 1148-1157.
Ma, Z., Liu, Q., Yang, H., Runyan, R. B., Eisenberg, C. A., Xu, M., Borg, T. K., Markwald, R., Wang, Y., Gao, B. Z. (2013). Laser patterning for the study of MSC cardiogenic differentiation at the single-cell level. Other. 2, .
Ma, Z., Yang, H., Liu, H., Xu, M., Runyan, R. B., Eisenberg, C. A., Markwald, R. R., Borg, T. K., Gao, B. Z. (2013). Mesenchymal Stem Cell-Cardiomyocyte Interactions under Defined Contact Modes on Laser-Patterned Biochips. PLOS One. 8(2), .
Ma, Z., Liu, Q., Liu, H., Yang, H., Yun, J. X., Xu, M., Eisenberg, C. A., Borg, T. K., Markwald, R., Gao, B. Z. (2012). Cardiogenic Regulation of Stem-Cell Electrical Properties in a Laser-Patterned Biochip. Other. 5(3), 327-336.
Ma, Z., Liu, Q., Liu, H., Yang, H., Yun, J. X., Eisenberg, C., Borg, T. K., Xu, M., Gao, B. Z. (2012). Laser-patterned stem-cell bridges in a cardiac muscle model for on-chip electrical conductivity analyses. Other. 12(3), 566-573.
Yang, H., Ma, Z. (2012). Microsystem for Stem Cell-Based Cardiovascular Research. Other. 2(4), 305-315.
Sun Min,, Yang Huaxiao,, Zhou Ping,, Pan Luanfeng,, Liu Shui, (2010). BIOCOMPATIBILITY OF PHBHHx AND SILK FIBROIN-MODIFIED PHBHHx SCAFFOLDS WITH HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS. Other. (12), 1430-1436.
Yang, H., Sun, M., Zhou, P. (2009). Investigation of water diffusion in poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) by generalized two-dimensional correlation ATR-FTIR spectroscopy. Polymer. 50(6), 1533-1540.
Review
Wnorowski, A., Yang, H., Wu, J. C. (2019). Progress, obstacles, and limitations in the use of stem cells in organ-on-a-chip models. Other. 140, 3-11.

Awarded Grants

Contracts, Grants and Sponsored Research

Fellowship
Yang, H., "Interrogating the Cardiovascular Toxicity of Volatile Organic Compounds from E-Cigarettes in hiPSC-derived Vascularized Cardiac Organoids," Sponsored by American Heart Association (AHA), National, $155716 Funded. (20182020).
Grant - Research
Yang, H., Tune, J., Albert, M., "Clinical trial in a dish for studying antihypertensive drug induced cardiovascular malformation and dysfunction in gestational hypertension," Sponsored by University of North Texas, University of North Texas, $7800 Funded. (20212022).
,
Overall
Summative Rating
Challenge and
Engagement Index
Response Rate

out of 5

out of 7
%
of
students responded
  • Overall Summative Rating (median):
    This rating represents the combined responses of students to the four global summative items and is presented to provide an overall index of the class’s quality. Overall summative statements include the following (response options include a Likert scale ranging from 5 = Excellent, 3 = Good, and 1= Very poor):
    • The course as a whole was
    • The course content was
    • The instructor’s contribution to the course was
    • The instructor’s effectiveness in teaching the subject matter was
  • Challenge and Engagement Index:
    This rating combines student responses to several SPOT items relating to how academically challenging students found the course to be and how engaged they were. Challenge and Engagement Index items include the following (response options include a Likert scale ranging from 7 = Much higher, 4 = Average, and 1 = Much lower):
    • Do you expect your grade in this course to be
    • The intellectual challenge presented was
    • The amount of effort you put into this course was
    • The amount of effort to succeed in this course was
    • Your involvement in course (doing assignments, attending classes, etc.) was
CLOSE