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Oluwatosin Oluwadare

Title: Associate Professor

Department: Computer Science and Engineering

College: College of Engineering

Curriculum Vitae

Curriculum Vitae Link

Education

  • PhD, University of Missouri - Columbia, 2019
    Major: Computer Science
  • MS, University of Texas at Arlington, 2015
    Major: Computer Science
    Dissertation: Gait Analysis on a Smart Floor for Health Monitoring

Current Scheduled Teaching

CSCE 3201.400Applied Artificial IntelligenceSpring 2026 Syllabus
CSCE 5218.400Deep LearningSpring 2026 Syllabus
CSCE 6940.982Individual ResearchSpring 2026

Previous Scheduled Teaching

CSCE 5934.882Directed StudyFall 2025
CSCE 6940.882Individual ResearchFall 2025

Published Intellectual Contributions

    Conference Proceeding

  • Akpokiro, V., Oluwadare, O., Kalita, J. (2021). DeepSplicer: An Improved Method of Splice Sites Prediction using Deep Learning. 2021 20th IEEE International Conference on Machine Learning and Applications (ICMLA). 606-609. IEEE. https://doi.org/10.1109/icmla52953.2021.00101
  • Journal Article

  • Chowdhury, H.M., Fuller, M., Oluwadare, O. (2026). Robin: an advanced tool for comparative loop caller result analysis leveraging large language models. Other. 8 (1) Oxford University Press (OUP). https://doi.org/10.1093/nargab/lqag009
  • Menon, R., Mohit Chowdhury, H., Oluwadare, O. (2025). ScHiCAtt: Enhancing single-cell Hi-C data resolution using attention-based models. Other. 27 978-991. Elsevier BV. https://doi.org/10.1016/j.csbj.2025.02.031
  • Chowdhury, H.M., Oluwadare, O. (2025). EmbedTAD Using Graph Embedding and Unsupervised Learning to Identify TADs from High-Resolution Hi-C Data. Other. 9 (1) Springer Science and Business Media LLC. https://doi.org/10.1038/s42003-025-09224-z
  • Olowofila, S., Oluwadare, O. (2025). DiCARN-DNase: enhancing cell-to-cell Hi-C resolution using dilated cascading ResNet with self-attention and DNase-seq chromatin accessibility data.. Other. 41 (9)
  • Chandrashekar MKB, Menon, R., Olowofila, S., Oluwadare, O. (2025). Unicorn: enhancing single-cell Hi-C data with blind super-resolution for 3D genome structure reconstruction.. Other. 41 (Supplement_1) i475-i483.
  • Pinchuk, D., Chowdhury, H.M., Pandeya, A., Oluwadare, O., Alkan, C. (2025). HiCForecast: dynamic network optical flow estimation algorithm for spatiotemporal Hi-C data forecasting. Other. 41 (2) Oxford University Press (OUP). https://doi.org/10.1093/bioinformatics/btaf030
  • Reckard, A.T., Pandeya, A., Voris, J.M., Gonzalez Cruz, C.G., Oluwadare, O., Klocko, A.D. (2024). A constitutive heterochromatic region shapes genome organization and impacts gene expression in Neurospora crassa. BMC Genomics. 25 (1) Springer Science and Business Media LLC. https://doi.org/10.1186/s12864-024-11110-7
  • Houchens, D., Chowdhury, H.M., Oluwadare, O. (2024). coiTAD: Detection of Topologically Associating Domains Based on Clustering of Circular Influence Features from Hi-C Data. Other. 15 (10) 1293. MDPI AG. https://doi.org/10.3390/genes15101293
  • Chowdhury, H.M., Boult, T., Oluwadare, O. (2024). Comparative study on chromatin loop callers using Hi-C data reveals their effectiveness. BMC Bioinformatics. 25 (1) Springer Science and Business Media LLC. https://doi.org/10.1186/s12859-024-05713-w
  • Akpokiro, V., Chowdhury, H.M., Olowofila, S., Nusrat, R., Oluwadare, O. (2023). CNNSplice: Robust models for splice site prediction using convolutional neural networks. Other. 21 3210-3223. American Association for the Advancement of Science (AAAS). https://doi.org/10.1016/j.csbj.2023.05.031
  • Vadnais, D., Oluwadare, O. (2023). ParticleChromo3D+: A Web Server for ParticleChromo3D Algorithm for 3D Chromosome Structure Reconstruction. Other. 45 (3) 2549-2560. MDPI AG. https://doi.org/10.3390/cimb45030167
  • Hovenga, V., Kalita, J., Oluwadare, O. (2022). HiC-GNN: A generalizable model for 3D chromosome reconstruction using graph convolutional neural networks.. Other. 21 812-836.
  • Higgins, S., Akpokiro, V., Westcott, A., Oluwadare, O. (2022). TADMaster: a comprehensive web-based tool for the analysis of topologically associated domains.. BMC Bioinformatics. 23 (1) 463.
  • Akpokiro, V., Martin, T., Oluwadare, O. (2022). EnsembleSplice: ensemble deep learning model for splice site prediction. BMC Bioinformatics. 23 (1) Springer Science and Business Media LLC. https://doi.org/10.1186/s12859-022-04971-w
  • Hicks, P., Oluwadare, O., Robinson, P. (2022). HiCARN: resolution enhancement of Hi-C data using cascading residual networks. Other. 38 (9) 2414-2421. Oxford University Press (OUP). https://doi.org/10.1093/bioinformatics/btac156
  • Collins, B., Oluwadare, O., Brown, P. (2021). ChromeBat: A Bio-Inspired Approach to 3D Genome Reconstruction. Other. 12 (11) 1757. MDPI AG. https://doi.org/10.3390/genes12111757
  • Hovenga, V., Oluwadare, O. (2021). CBCR: A Curriculum Based Strategy For Chromosome Reconstruction. International Journal of Molecular Sciences. 22 (8) 4140. MDPI AG. https://doi.org/10.3390/ijms22084140
  • Oluwadare, O., Highsmith, M., Turner, D., Lieberman Aiden, E., Cheng, J. (2020). GSDB: a database of 3D chromosome and genome structures reconstructed from Hi-C data. Other. 21 (1) Springer Science and Business Media LLC. https://doi.org/10.1186/s12860-020-00304-y
  • Oluwadare, O., Highsmith, M., Turner, D., Lieberman Aiden, E., Cheng, J. (2020). Correction to: GSDB: a database of 3D chromosome and genome structures reconstructed from Hi-C data.. Other. 21 (1) 62.
  • Oluwadare, O., Highsmith, M., Cheng, J. (2019). An Overview of Methods for Reconstructing 3-D Chromosome and Genome Structures from Hi-C Data. Other. 21 (1) Springer Science and Business Media LLC. https://doi.org/10.1186/s12575-019-0094-0
  • Trieu, T., Oluwadare, O., Wopata, J., Cheng, J. (2019). GenomeFlow: a comprehensive graphical tool for modeling and analyzing 3D genome structure.. Other. 35 (8) 1416-1418.
  • Oluwadare, O., Zhang, Y., Cheng, J. (2018). A maximum likelihood algorithm for reconstructing 3D structures of human chromosomes from chromosomal contact data. BMC Genomics. 19 (1) Springer Science and Business Media LLC. https://doi.org/10.1186/s12864-018-4546-8
  • Oluwadare, O., Cheng, J. (2017). ClusterTAD: an unsupervised machine learning approach to detecting topologically associated domains of chromosomes from Hi-C data. BMC Bioinformatics. 18 (1) Springer Science and Business Media LLC. https://doi.org/10.1186/s12859-017-1931-2
  • Nowotny, J., Wells, A., Oluwadare, O., Xu, L., Cao, R., Trieu, T., He, C., Cheng, J. (2016). GMOL: An Interactive Tool for 3D Genome Structure Visualization. Scientific Reports. 6 (1) Springer Science and Business Media LLC. https://doi.org/10.1038/srep20802
  • Nowotny, J., Ahmed, S., Xu, L., Oluwadare, O., Chen, H., Hensley, N., Trieu, T., Cao, R., Cheng, J. (2015). Iterative reconstruction of three-dimensional models of human chromosomes from chromosomal contact data.. BMC Bioinformatics. 16 338.
  • Research/Creativity Activity Cited by Other Scholars

  • Olowofila, S., Oluwadare, O. (2024). DiCARN-DNase: Enhancing Cell-to-Cell Hi-C Resolution Using Dilated Cascading ResNet with Self-Attention and DNase-seq Chromatin Accessibility Data. openRxiv. https://doi.org/10.1101/2024.10.31.621380
  • Menon, R., Chowdhury, H.M., Oluwadare, O. (2024). ScHiCAtt: Enhancing Single-Cell Hi-C Resolution Using Attention-Based Models. openRxiv. https://doi.org/10.1101/2024.12.16.628505
  • Vadnais, D., Middleton, M., Oluwadare, O. (2021). ParticleChromo3D: A Particle Swarm Optimization Algorithm for Chromosome and Genome 3D Structure Prediction from Hi-C Data. openRxiv. https://doi.org/10.1101/2021.02.11.430871
  • Highsmith, M., Oluwadare, O., Cheng, J. (2019). Deep Learning For Denoising Hi-C Chromosomal Contact Data. openRxiv. https://doi.org/10.1101/692558
  • posted-content

  • Thapa, S., Tamargo, M., Oluwadare, O. ASPECT: Alternative Splicing Event Classification with Transformers. openRxiv. https://doi.org/10.64898/2026.02.04.700904
  • Mohit Chowdhury, H.M., Oluwadare, O. HiCInterpolate: 4D Spatiotemporal Interpolation of Hi-C Data for Genome Architecture Analysis. openRxiv. https://doi.org/10.64898/2026.02.06.704438
  • Reckard, A.T., Pandeya, A., Voris, J.M., Gonzalez Cruz, C.G., Oluwadare, O., Klocko, A.D. (2024). A Constitutive Heterochromatic Region Shapes Genome Organization and Impacts Gene Expression in Neurospora crassa. openRxiv. https://doi.org/10.1101/2024.06.07.597955
  • Hovenga, V., Kalita, J., Oluwadare, O. (2022). 3D chromosome structure reconstruction using graph convolutional neural networks. F1000 Research Ltd. https://doi.org/10.7490/f1000research.1119247.1
  • Van Hovenga, Oluwadare, O., Kalita, J. (2021). HiC-GNN: A Generalizable Model for 3D Chromosome Reconstruction Using Graph Convolutional Neural Networks. openRxiv. https://doi.org/10.1101/2021.11.29.470405
  • Trieu, T., Oluwadare, O., Cheng, J. (2019). Hierarchical Reconstruction of High-Resolution 3D Models of Human Chromosomes. openRxiv. https://doi.org/10.1101/415810

Contracts, Grants and Sponsored Research

    Grant - Research

  • Oluwadare, O. (Principal), "Can one size fit all? - High-Resolution 3D Genome Spatial Organization Inference with Generalizable Models," sponsored by National Institute of Health, Federal, $1007407 Funded. (2025 - 2028).
  • Oluwadare, O. (Principal), "Can one size fit all? – High-Resolution 3D Genome Spatial Organization Inference with Generalizable Models," sponsored by National Institute of Health, Federal, $1611219 Funded. (2023 - 2028).
  • Macias, V.M. (Principal), Baxter-Slye, J.L. (Co-Principal), Junker, J. (Co-Principal), Oluwadare, O. (Co-Principal), "Artificial Intelligence and the Classical Entomologist: Designing interdisciplinary pedagogy to revive an essential, but dying art-(Start date January 16th 2025)," sponsored by Learning Institutes, University of North Texas, $5000 Funded. (2025 - 2026).
  • Oluwadare, O.E. (Co-Principal), "CyberRangerForge: A University of Colorado System Virtual Institute for Cyber Range and Research based Advanced Training of ROTC Cadets for Next Generation Cyber Operations," sponsored by Griffiss Institute, Private, $1500000 Funded. (2023 - 2025).
  • Oluwadare, O. (Principal), ""CRII:III:Development of deep learning methods for high-resolution 3D genomestructure spatial reconstruction," sponsored by National Science Foundation, Federal, $175000 Funded. (2022 - 2025).
  • Oluwadare, O. (Co-Principal), "REU Site: Deep Learning: Theory, Concepts and Applications," sponsored by National Science Foundation, Federal, $404980 Funded. (2021 - 2024).
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Overall
Summative Rating
Challenge and
Engagement Index
Response Rate

out of 5

out of 7
%
of
students responded
  • Overall Summative Rating (median):
    This rating represents the combined responses of students to the four global summative items and is presented to provide an overall index of the class’s quality. Overall summative statements include the following (response options include a Likert scale ranging from 5 = Excellent, 3 = Good, and 1= Very poor):
    • The course as a whole was
    • The course content was
    • The instructor’s contribution to the course was
    • The instructor’s effectiveness in teaching the subject matter was
  • Challenge and Engagement Index:
    This rating combines student responses to several SPOT items relating to how academically challenging students found the course to be and how engaged they were. Challenge and Engagement Index items include the following (response options include a Likert scale ranging from 7 = Much higher, 4 = Average, and 1 = Much lower):
    • Do you expect your grade in this course to be
    • The intellectual challenge presented was
    • The amount of effort you put into this course was
    • The amount of effort to succeed in this course was
    • Your involvement in course (doing assignments, attending classes, etc.) was
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