Pamela A. Padilla

Previous Scheduled Teaching

Published Intellectual Contributions

Book Chapter

• Padilla, P.A., Goy, J.M., Hajari, V.A. (2011). Anoxia-induced suspended animation in Caenorhabditis elegans in Anoxia.

Conference Proceeding

• Satumtira, N.T., Marpu, S., Stewart, A., Padilla, P.A., Neogi, P.B., Turnbull, L., Omary, M.A. (2009). Oxygen indication in biological models using a highly luminescent platinum complex:(K-4 [Pt-2 (P2O5H2)(4)] center dot 2H (2) O). ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 238

Journal Article

• Burggren, W.W., Padilla, P.A., Martinez Bautista, G. Genetic Basis for Morphological Variation in the Zebrafish Danio. Fishes.
• King, S.D., Gray, C.F., Song, L., Mittler, R., Padilla, P.A. (2021). The mitochondrial localized CISD-3.1/CISD-3.2 proteins are required to maintain normal germline structure and function in Caenorhabditis elegans. PLOS One. 16 (2) Denton, https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0245174
• Bautista, N., Crespel, A., Padilla, P.A., Crossley, J., Burggren, W.W. (2020). Parental Transgenerational epigenetic inheritance related to dietary crude oil exposure in Danio rerio. Journal of Experimental Biology. jeb.222224.
• King, S.D., Gray, C.F., Song, L., Nechushtai, R., Gumienny, T.L., Mittler, R., Padilla, P.A. (2019). The cisd gene family regulates physiological germline apoptosis through ced-13 and the canonical cell death pathway in Caenorhabditis elegans. Other. 26 (1) 162-178. Nature. https://www.nature.com/articles/s41418-018-0108-5
• Sengupta, S., Nechushtai, R., Jennings, P.A., Onuchic, J.N., Padilla, P.A., Azad, R., Mittler, R. (2018). Phylogenetic analysis of the CDGSH iron-sulfur binding domain reveals its ancient origin. Scientific Reports. 8
• Inupakutika, M.A., Sengupta, S., Nechushtai, R., Jennings, P.A., Onuchic, J.N., Azad, R.K., Padilla, P.A., Mittler, R. (2017). Phylogenetic analysis of eukaryotic NEET proteins uncovers a link between a key gene duplication event and the evolution of vertebrates.. Scientific Reports. 7 42571.
• Verbeck, G.F., Hamilton, J., Gorishek, E., Mach, P., Sturtevant, D., Ladage, M., Suzuki, N., Padilla, P.A., Mittler, R., Chapman, K.D. (2016). Evaluation of a custom single Peltier-cooled ablation cell for elemental imaging of biological samples in laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS). 31 1030-1033.
• Ladage, M.L., King, S.D., Burks, D.J., Quan, D.L., Garcia, A.M., Azad, R.K., Padilla, P.A. (2016). Glucose or Altered Ceramide Biosynthesis Mediate Oxygen Deprivation Sensitivity Through Novel Pathways Revealed by Transcriptome Analysis in Caenorhabditis elegans.. G3: Genes, Genomes, Genetics. 6 (10) 3149-3160.
• Toni, L.S., Padilla, P.A. (2016). Developmentally arrested Austrofundulus limnaeus embryos have changes in post-translational modifications of histone H3.. The Journal of Experimental Biology. 219 (Pt 4) 544-52.
• Kanteti, R., Dhanasingh, I., El-Hashani, E., Riehm, J.J., Stricker, T., Nagy, S., Zaborin, A., Zaborina, O., Biron, D., Alverdy, J.C., Im, H.K., Siddiqui, S., Padilla, P.A., Salgia, R. (2016). C. elegans and mutants with chronic nicotine exposure as a novel model of cancer phenotype.. Cancer Biology & Therapy. 17 (1) 91-103.
• Garcia, A.M., Ladage, M.L., Dumesnil, D.R., Zaman, K., Shulaev, V., Azad, R.K., Padilla, P.A. (2015). Glucose induces sensitivity to oxygen deprivation and modulates insulin/IGF-1 signaling and lipid biosynthesis in Caenorhabditis elegans.. Genetics. 200 (1) 167-84.
• Padmanabha, D., Padilla, P.A., You, Y.J., Baker, K. (2015). A HIF-independent mediator of transcriptional responses to oxygen deprivation in Caenorhabditis elegans.. Genetics. 199 (3) 739-48.
• Padilla, P.A., Garcia, A.M., Ladage, M.L., Toni, L.S. (2014). Caenorhabditis elegans: an old genetic model can learn new epigenetic tricks.. Integrative and Comparative Biology. 54 (1) 52-60.
• LaRue, C.C., Padilla, P.A. (2012). IBI series winner. A mutant search--Caenorhabditis elegans and gene discovery.. Other. 338 (6106) 487-8.
• Padilla, P.A., Ladage, M.L. (2012). Suspended animation, diapause and quiescence: arresting the cell cycle in C. elegans.. Other. 11 (9) 1672-9.
• Garcia, A.M., Ladage, M.L., Padilla, P.A. (2011). Use of Time Lapse Microscopy to Visualize Anoxia-induced Suspended Animation in C. elegans Embryos. Journal of Visualized Experiments. (70) MyJove Corporation. http://dx.doi.org/10.3791/4319
• LaRue, B.L., Padilla, P.A. (2011). Environmental and genetic preconditioning for long-term anoxia responses requires AMPK in Caenorhabditis elegans.. PLOS One. 6 (2) e16790.
• Hajeri, V.A., Little, B.A., Ladage, M.L., Padilla, P.A. (2010). NPP-16/Nup50 function and CDK-1 inactivation are associated with anoxia-induced prophase arrest in Caenorhabditis elegans.. Molecular Biology of the Cell. 21 (5) 712-24.
• Mendenhall, A.R., LeBlanc, M.G., Mohan, D.P., Padilla, P.A. (2009). Reduction in ovulation or male sex phenotype increases long-term anoxia survival in a daf-16-independent manner in Caenorhabditis elegans.. Physiological Genomics. 36 (3) 167-78.
• Jud, M.C., Czerwinski, M.J., Wood, M.P., Young, R., Gallo, C.M., Bickel, J.S., Petty, E.L., Mason, J.M., Little, B.A., Padilla, P.A., Schisa, J.A. (2008). Large P body-like RNPs form in C. elegans oocytes in response to arrested ovulation, heat shock, osmotic stress, and anoxia and are regulated by the major sperm protein pathway.. Developmental Biology. 318 (1) 38-51.
• Hajeri, V.A., Stewart, A.M., Moore, L.L., Padilla, P.A. (2008). Genetic analysis of the spindle checkpoint genes san-1, mdf-2, bub-3 and the CENP-F homologues hcp-1 and hcp-2 in Caenorhabditis elegans.. Cell Division. 3 6.
• Mendenhall, A.R., LaRue, B., Padilla, P.A. (2006). Glyceraldehyde-3-phosphate dehydrogenase mediates anoxia response and survival in Caenorhabditis elegans.. Genetics. 174 (3) 1173-87.
• Hajeri, V.A., Trejo, J., Padilla, P.A. (2005). Characterization of sub-nuclear changes in Caenorhabditis elegans embryos exposed to brief, intermediate and long-term anoxia to analyze anoxia-induced cell cycle arrest.. BMC Cell Biology. 6 47.
• Nystul, T.G., Goldmark, J.P., Padilla, P.A., Roth, M.B. (2003). Suspended animation in C. elegans requires the spindle checkpoint.. Other. 302 (5647) 1038-41.
• Padilla, P.A., Nystul, T.G., Zager, R.A., Johnson, A.C., Roth, M.B. (2002). Dephosphorylation of cell cycle-regulated proteins correlates with anoxia-induced suspended animation in Caenorhabditis elegans.. Molecular Biology of the Cell. 13 (5) 1473-83.
• P.A. Padilla and M.B. Roth. (2001). Oxygen deprivation causes suspended animation in the zebrafish embryo.
• P.A. Padilla, E.K. Fuge, M. E. Crawford, A. Errett, M. Werner-Washburne. (1998). The highly conserved, coregulated SNO and SNZ gene families in Saccharomyces cerevisiae respond to nutrient limitation.
• V.M. Peck, E.K. Fuge, P.A. Padilla, M.A. Gomez, M. Werner-Washburne. (1997). Yeast bcy1 mutants with stationary phase-specific defects.
• E.L. Braun, E.K. Fuge, P.A. Padilla, M. Werner-Washburne. (1996). A stationary-phase gene in Saccharomyces cerevisiae is a member of a novel, highly conserved gene family.

Popular Press Article

• Padilla, P.A. (2005). A Hand Up-Women Mentoring Women in Science.

Contracts, Grants and Sponsored Research

Grant - Research

• Padilla, P.A. (Principal), Stuart, K.L. (Other), Ryals, A.J. (Other), "UNT GRISE T-32 Awarded to Kara Stuart (Graduate Student)," sponsored by NIH sponsored by the UNT College of Science, University of North Texas, $80000 Funded. (2021).
• Padilla, P.A. (Principal), Burggren, W.W. (Co-Principal), Hughes, L.E. (Co-Principal), Cisneros, G. (Co-Principal), "G-RISE at UNT," sponsored by National Institutes of Health - NIGMS, Federal, $2187228 Funded. (2021 - 2026).
• Padilla, P.A. (Principal), Mittler, R. (Co-Principal), "Regulation of Mitochondrial Functions by Iron and Ceramides in C. elegans," sponsored by National Science Foundation, Federal, $992743 Funded. (2016 - 2021).
• Azad, R.K. (Principal), Padilla, P.A. (Principal), "Molecular consequences of glucose diet and altered ceramide species impacting oxygen deprivation responses," sponsored by National Institutes of Health, Federal, $445343 Funded. (2016 - 2020).
• Padilla, P.A. (Principal), "CAREER: Use of C. elegans to Identify Alleles and Genotypes that Modulate Severe Anoxia Survival," sponsored by National Sciences Foundation, Federal, $639556 Funded. (2008 - 2013).
• Padilla, P. (Principal), "Genetic and Cellular Analysis of C. elegans Exposed to Anoxia," sponsored by National Institutes of Health (RO1 GM069419-01A1), NIGMS, Federal, $894409 Funded. (2004 - 2009).
• Padilla, P.A. (Co-Principal), Burggren, W.W. (Principal), "Non-Genetic Inheritance of Hypoxia Tolerance in Fishes: Dynamics and Mechanisms," sponsored by National Science Foundation, FED, Funded. (2021 - 2025).
• Padilla, P.A. (Principal), "Regulation of Mitochondrial Functions by Iron and Ceramides in C. elegans," sponsored by National Science Foundation, FED, Funded. (2016 - 2022).
• Cisneros, G.A. (Co-Principal), Hughes, L.E. (Co-Principal), Padilla, P.A. (Principal), Burggren, W.W. (Co-Principal), "G-RISE at the University of North Texas," sponsored by National Institutes of Health, FED, Funded. (2021 - 2022).
• Padilla, P.A. (Principal), Azad, R.K. (Co-Principal), "Molecular Consequences of Glucose Diet and Altered Ceramide Species Impacting Oxygen Deprivation Responses," sponsored by National Institutes of Health, FED, Funded. (2016 - 2020).
• Padilla, P.A. (Co-Principal), Burggren, W.W. (Principal), "Epigenetic Inheritance of Physiological Phenotypes: Occurrence, Mechanism and Inter- and Intra-Individual Variation," sponsored by National Science Foundation, FED, Funded. (2015 - 2019).
• Padilla, P.A. (Principal), "CAREER: Use of C. elegans to Identify Alleles and Genotypes that Modulate Severe Anoxia Survival," sponsored by National Sciences Foundation, Federal, Funded. (2008 - 2013).
• Padilla, P. (Principal), "Genetic and Cellular Analysis of C. elegans Exposed to Anoxia," sponsored by National Institutes of Health (RO1 GM069419-01A1), NIGMS, Federal, Funded. (2004 - 2009).

Grant - Service

• Padilla, P.A. (Principal), Welch, C. (Co-Principal), Silveyra, P. (Co-Principal), "Culturally Responsive Academic and Career Trainings to Diversify the Biomedical Workforce -SACNAS R25 GM130515-01A1," sponsored by National Institutes of Health, Federal, $2420935 Funded. (2020 - 2025).
• Hunt von Herbing, I. (Co-Principal), Padilla , P. (Principal), Golden, T.D. (Co-Principal), Lund, A.K. (Co-Principal), Philipose, U. (Co-Principal), Wang, X., "Women in Science Mentoring Group: Team Mentoring Grant (renewed for a second year - $5000 per year)," sponsored by University of North Texas, University of North Texas, $10000 Funded. (2018 - 2020).
• Padilla, P.A. (Principal), Welch, C. (Co-Principal), Silveyra, P. (Co-Principal), "Culturally Responsive Academic and Career Trainings to Diversify the Biomedical Workforce -SACNAS R25 GM130515-01A1," sponsored by National Institutes of Health, Federal, Funded. (2020 - 2025).

Grant - Teaching

• Hughes, L.E. (Principal), Padilla, P.A. (Co-Principal), "Fostering Outstanding Cohorts in Undergraduate Science II," sponsored by National Science Foundation, FED, Funded. (2013 - 2019).