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Xiaoqiang Wang

Title: Research Associate Professor

Department: Biological Sciences

College: College of Science

Curriculum Vitae

Curriculum Vitae Link

Education

  • PhD, Chinese Academy of Sciences, 1993
    Major: Protein Crystallography/Molecular Biology
  • MS, Wuhan University, 1990
    Major: Chemistry
  • BS, Wuhan University, 1987
    Major: Chemistry

Current Scheduled Teaching

BIOL 4900.761Special ProblemsSpring 2025
BIOL 4900.761Special ProblemsFall 2024

Previous Scheduled Teaching

BIOL 4900.761Special ProblemsSummer 10W 2024
BIOL 4900.761Special ProblemsSpring 2024
BIOL 4900.761Special ProblemsFall 2023
BIOC 5950.761Master's ThesisSummer 5W2 2023
BIOL 4900.761Special ProblemsSummer 10W 2023
BIOL 6940.761Individual ResearchFall 2022
BIOC 5950.761Master's ThesisSummer 5W2 2022
BIOC 5950.761Master's ThesisSpring 2022
BIOC 5900.761Special ProblemsSpring 2021
BIOL 4900.761Special ProblemsSpring 2021
BIOL 4900.761Special ProblemsFall 2020
BIOL 4900.761Special ProblemsSpring 2020
BIOL 4900.761Special ProblemsSummer 10W 2019
BIOL 4900.761Special ProblemsSpring 2019
BIOL 6940.761Individual ResearchFall 2018
BIOL 4900.761Special ProblemsFall 2018
BIOL 4910.761Special ProblemsFall 2018
BIOL 4900.761Special ProblemsSpring 2018

Published Intellectual Contributions

    Book Chapter

  • Alderete, K., Wang, X. (2022). Structural determination of uridine diphosphate glycosyltransferases using X-ray crystallography. Methods in molecular biology (Clifton, N.J.). 2396 227-241. New York, NY, Humana.
  • Journal Article

  • Cheng, N., Paris, V., Rao, X., Wang, X., Nakata, P. (2022). A conserved oxalyl-Coenzyme A decarboxylase in oxalate catabolism. Plant Signaling & Behavior. 17 2062555.
  • Wang, X., Pan, H., Sagurthi, S., Paris, V., Zhuo, C., Dixon, R. (2022). The protein conformational basis of isoflavone biosynthesis.. Other. 5 (1) 1249.
  • Zhuo, C., Wang, X., Docampo-Palacios, M., Sanders, B.C., Engle, N.L., Tschaplinski, T.J., Hendry, J.I., Maranas, C.D., Chen, F., Dixon, R. (2022). Developmental changes in lignin composition are driven by both monolignol supply and laccase specificity.. Science Advances. 8 (10) eabm8145.
  • Foster, J., Chen, N., Paris, V., Wang, L., Wang, J., Wang, X., Nakata, P. (2021). An Arabidopsis oxalyl-CoA decarboxylase, AtOXC, is important for oxalate catabolism in plants. International Journal of Molecular Sciences. 22 3266.
  • Jun, J.H., Lu, N., Docampo-Palacios, M., Wang, X., Dixon, R. (2021). Dual activity of anthocyanidin reductase supports the dominant plant proanthocyanidin extension unit pathway.. Science Advances. 7 (20)
  • Adiji, O.A., Docampo-Palacios, M.L., Alvarez-Hernandez, A., Pasinetti, G.M., Wang, X., Dixon, R. UGT84F9 is the major flavonoid UDP-glucuronosyltransferase in Medicago truncatula.. Plant Physiology.
  • Wang, X., Zhuo, C., Xiao, X., Wang, X., Docampo-Palacios, M.L., Chen, F., Dixon, R. (2020). Substrate-Specificity of LACCASE 8 Facilitates Polymerization of Caffeyl Alcohol for C-Lignin Biosynthesis in the Seed Coat of Cleome hassleriana.. The Plant Cell. 32 3825-3845.
  • Aziz, M., Wang, X., Tripathi, A., Bankaitis,, V.A., Chapman, K.D. (2019). Structural analysis of a plant fatty acid amide hydrolase provides insights into the evolutionary diversity of bioactive acylethanolamides.. Journal of Biological Chemistry.
  • Aziz, M., Wang, X., Tripathi, A., Bankaitis, V.A., Chapman, K.D. (2019). Structural analysis of a plant fatty acid amide hydrolase provides insights into the evolutionary diversity of bioactive acylethanolamides. Journal of Biological Chemistry. 294 (18) 7419-7432. American Society for Biochemistry & Molecular Biology (ASBMB). http://dx.doi.org/10.1074/jbc.ra118.006672
  • Zhuo, C., Rao, X., Azad, R.K., Pandey, R., Xiao, X., Harkelroad, A., Wang, X., Chen, F., Dixon, R. (2019). Enzymatic basis for C-lignin monomer biosynthesis in the seed coat of Cleome hassleriana.. The Plant journal : for cell and molecular biology. 99 506-520.
  • He, Y., Zhou, L., Gao, S., Yin, T., Tu, Y., Wang, X., Rayford, R., Hu, M. (2018). Development and validation of a sensitive LC-MS/MS method for simultaneous determination of eight tyrosine kinase inhibitors and its application in mice pharmacokinetic studies. Journal of Pharmaceutical and Biomedical Analysis. 148 65-72.
  • Pan, Z., Baerson, S.R., Wang, M., Bajsa-Hirschel, J., Rimando, A.M., Wang, X., Nanayakkara, N.P., Noonan, B.P., Fromm, M.E., Dayan, F.E., Khan, I., Duke, S.O. (2018). Sorghum cytochrome P450 CYP71AM1 catalyzes the conversion of pentadecatrienyl resorcinol to dihydrosorgoleone in sorgoleone biosynthesis. New Phytologist. 218 616-629.
  • Docampo, M., Olubu, A., Wang, X., Pasinetti, G., Dixon, R. (2017). Glucuronidated flavonoids in neurological protection: structural analysis and approaches for chemical and biological synthesis. Journal of Agricultural and Food Chemistry. 65 7607-7623.
  • Liu, C., Wang, X., Shulaev, V., Dixon, R. (2016). A role for leucoanthocyanidin reductase in the extension of proanthocyanidins.. Nature Plants. 2 16182.
  • Wu, X., Wu, F.H., Wang, X., Wang, L., Siedow, J.N., Zhang, W., Pei, Z.M.. (2014).
  • Pan, H., Zhou, R., Louie, G.V., Mühlemann, J.K., Bomati, E.K., Bowman, M.E., Dudareva, N., Dixon, R.A., Noel, J.P., Wang, X.. (2014).
  • Zhao, Q., Nakashima, J., Chen, F., Yin, Y., Fu, C., Yun, J., Shao, H., Wang, X., Wang, Z., Dixon, R.. (2013).
  • Wu, B., Wang, X., Zhang, S., Hu, M.. (2012).
  • Wu, B., Basu, S., Meng, S., Wang, X., Hu, M.. (2011).
  • Li, L., Cheng, N., Hirschi, K.D., Wang, X.. (2010).
  • Modolo, L.V., Escamilla-Trevino L.L., Dixon, R.A., Wang, X.. (2009).
  • Modolo, L.V., Li, L., Pan, H., Blount, J.W., Dixon, R.A., Wang, X.. (2009).
  • Wang, X.. (2009).
  • Li, L., Chang, Z., Pan, Z., Fu, Z., Wang, X.. (2008).
  • Shao, H., Dixon, R.A., Wang, X.. (2007).
  • Li, L., Modolo, L.V., Escamilla-Trevino L.L., Achnine, L., Dixon, R.A., Wang, X.. (2007).
  • Modolo, L.V., Blount, J.W., Achnine, L., Naoumkina, M.A., Wang, X., Dixon, R.A.. (2007).
  • He, X., Wang, X., Dixon, R.A.. (2006).
  • Wang, X., He, X., Lin, J., Shao, H., Chang, Z., Dixon, R.A.. (2006).
  • Shao, H., He, X., Achnine, L., Blount, J.W., Dixon, R.A., Wang, X.. (2005).
  • Wang, X., McLachlan, J., Zamore, P.D., Hall, T.M.T.. (2002). Modular recognition of RNA by a human Pumilio-homology domain. Cell. 110 501-512.
  • Wang, X., Zamore, P.D., Hall, T.M.T.. (2001). Crystal structure of a Pumilio homology domain. Molecular Cell. 7 855-865.
  • Wang, X., Hall, T.M.T.. (2001). Structural basis for recognition of AU-rich element RNA by the HuD protein. Nature Structural Biology. 8 141-145.
  • Wang, X., Lin, X., Loy, J.A., Tang, J., Zhang, X.C.. (1998).
  • Wang, X., Wang, C., Tang, J., Dyda, F., Zhang, X.C.. (1997).
  • Wang, X., Yang, J., Gui, L., Lin, Z., Chen, Y., Zhou, Y.. (1996).
  • Xie, C., Wang, X., Song, Z., Qu, S., Wang, P., Quo, Z.. (1992).
  • Wang, X., Xie, C., Qu, S., Zhou, Z.. (1991).

Contracts, Grants and Sponsored Research

    Contract

  • Wang, X. (Principal), "Development of drug detoxifying bacteria for chemotherapy induced gut injury," sponsored by NIH, Federal, $140000 Funded. (2021 - 2023).
  • Wang, X. (Principal), "Enzyme design and engineering toward synthesis of bioactive products," sponsored by Conagen Inc, Private, $242502 Funded. (2018 - 2023).
  • Wang, X. (Principal), "Enzyme design and engineering toward synthesis of bioactive products," sponsored by Conagen Inc, Private, Funded. (2018 - 2022).
  • Grant - Research

  • Skellam, E.J., Wang, X., "Molecular and structural studies of the first fungal polyketide synthase / non-ribosomal peptide synthetase adenylation domain toward biomolecular probes design," sponsored by UNT BDI, University of North Texas, $10000 Funded. (2022).
  • Wang, X. (Principal), Nakata, P. (Co-Principal), "Structural and mechanistic studies of oxalate catabolism," sponsored by NSF, Federal, $800000 Funded. (2023 - 2026).
  • Chapman, K.D. (Principal), Wang, X. (Supporting), "Molecular targets and actions of ethanolamide oxylipins in Arabidopsis thaliana," sponsored by NSF Integrative Organismal Systems (IOS 1656263), Federal, $796365 Funded. (2017 - 2021).
  • Wang, X. (Principal), "UGT engineering for detoxifying anticancer drug SN-38," sponsored by NIH/NCI, Federal, $451570 Funded. (2015 - 2019).
  • Chan, T. (Supporting), Wang, X. (Principal), "Development of Drug Detoxifying Bacteria for Chemotherapy Induced Gut Injury," sponsored by Sanarentero LLC, IND, Funded. (2021 - 2022).
  • Chapman, K.D. (Principal), "Molecular Targets and Actions of Ethanolamide-Conjugated Oxylipins in Arabidopsis Thaliana," sponsored by National Science Foundation, FED, Funded. (2017 - 2021).
  • Longo, A. (Co-Principal), Wang, X. (Principal), "UGT Engineering for Detoxifying Anticancer Drug SN-38," sponsored by National Institutes of Health, FED, Funded. (2015 - 2019).
  • Grant - Service

  • Wang, X. (Principal), "Engineering glycosylation toward discovery of novel products and drugs," sponsored by UNT's I-GRO fund - Global Discovery Program, University of North Texas, $6000 Funded. (2014 - 2015).
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Overall
Summative Rating
Challenge and
Engagement Index
Response Rate

out of 5

out of 7
%
of
students responded
  • Overall Summative Rating (median):
    This rating represents the combined responses of students to the four global summative items and is presented to provide an overall index of the class’s quality. Overall summative statements include the following (response options include a Likert scale ranging from 5 = Excellent, 3 = Good, and 1= Very poor):
    • The course as a whole was
    • The course content was
    • The instructor’s contribution to the course was
    • The instructor’s effectiveness in teaching the subject matter was
  • Challenge and Engagement Index:
    This rating combines student responses to several SPOT items relating to how academically challenging students found the course to be and how engaged they were. Challenge and Engagement Index items include the following (response options include a Likert scale ranging from 7 = Much higher, 4 = Average, and 1 = Much lower):
    • Do you expect your grade in this course to be
    • The intellectual challenge presented was
    • The amount of effort you put into this course was
    • The amount of effort to succeed in this course was
    • Your involvement in course (doing assignments, attending classes, etc.) was
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