Xiaoqiang Wang

Previous Scheduled Teaching

Published Intellectual Contributions

Book Chapter

• Alderete, K., Wang, X. (2022). Structural determination of uridine diphosphate glycosyltransferases using X-ray crystallography. Methods in molecular biology (Clifton, N.J.). 2396 227-241. New York, NY, Humana.

Journal Article

• Zhuo, C., Wang, X., Shrestha, H.K., Abraham, P.E., Hettich, R.L., Chen, F., Barros, J., Dixon, R. (2024). Major facilitator family transporters specifically enhance caffeyl alcohol uptake during C-lignin biosynthesis in Cleome hassleriana. New Phytologist. 246 (4) 1520-1535. Lancaster, United Kingdom., Wiley-Blackwell. https://nph.onlinelibrary.wiley.com/doi/10.1111/nph.20325
• Lethe , M.C., Paris, V., Wang, X., Chan, T. (2024). Similarities in structure and function of UDP-glycosyltransferase homologs from human and plants. International Journal of Molecular Sciences. 25 (5) 2782. Basel, Switzerland, MDPI. PMCID: PMC10932239 PMID: 38474028
• Lethe, M.C., Bui , D.n., Hu, M.n., Wang, X., Singh, R.n., Chan, T. (2024). Discovering new substrates of a UDP-glycosyltransferase homologs from human and plants. International Journal of Molecular Sciences. 25 (5) 2725. Basel, Switzerland, Molecular Diversity Preservation International (MDPI). PMCID: PMC10931590 PMID: 38473971
• Cheng, N., Paris, V., Rao, X., Wang, X., Nakata, P. (2022). A conserved oxalyl-Coenzyme A decarboxylase in oxalate catabolism. Plant Signaling & Behavior. 17 2062555.
• Wang, X., Pan, H., Sagurthi, S., Paris, V., Zhuo, C., Dixon, R. (2022). The protein conformational basis of isoflavone biosynthesis.. Other. 5 (1) 1249.
• Zhuo, C., Wang, X., Docampo-Palacios, M., Sanders, B.C., Engle, N.L., Tschaplinski, T.J., Hendry, J.I., Maranas, C.D., Chen, F., Dixon, R. (2022). Developmental changes in lignin composition are driven by both monolignol supply and laccase specificity.. Science Advances. 8 (10) eabm8145.
• Foster, J., Chen, N., Paris, V., Wang, L., Wang, J., Wang, X., Nakata, P. (2021). An Arabidopsis oxalyl-CoA decarboxylase, AtOXC, is important for oxalate catabolism in plants. International Journal of Molecular Sciences. 22 3266.
• Jun, J.H., Lu, N., Docampo-Palacios, M., Wang, X., Dixon, R. (2021). Dual activity of anthocyanidin reductase supports the dominant plant proanthocyanidin extension unit pathway. Science Advances. 7 (20) American Association for the Advancement of Science (AAAS). https://doi.org/10.1126/sciadv.abg4682
• Jun, J.H., Lu, N., Docampo-Palacios, M., Wang, X., Dixon, R. (2021). Dual activity of anthocyanidin reductase supports the dominant plant proanthocyanidin extension unit pathway.. Science Advances. 7 (20)
• Adiji, O.A., Docampo-Palacios, M.L., Alvarez-Hernandez, A., Pasinetti, G.M., Wang, X., Dixon, R. UGT84F9 is the major flavonoid UDP-glucuronosyltransferase in Medicago truncatula.. Plant Physiology.
• Wang, X., Zhuo, C., Xiao, X., Wang, X., Docampo-Palacios, M.L., Chen, F., Dixon, R. (2020). Substrate-Specificity of LACCASE 8 Facilitates Polymerization of Caffeyl Alcohol for C-Lignin Biosynthesis in the Seed Coat of Cleome hassleriana.. The Plant Cell. 32 3825-3845.
• Aziz, M., Wang, X., Tripathi, A., Bankaitis,, V.A., Chapman, K.D. (2019). Structural analysis of a plant fatty acid amide hydrolase provides insights into the evolutionary diversity of bioactive acylethanolamides.. Journal of Biological Chemistry.
• Aziz, M., Wang, X., Tripathi, A., Bankaitis, V.A., Chapman, K.D. (2019). Structural analysis of a plant fatty acid amide hydrolase provides insights into the evolutionary diversity of bioactive acylethanolamides. Journal of Biological Chemistry. 294 (18) 7419-7432. American Society for Biochemistry & Molecular Biology (ASBMB). http://dx.doi.org/10.1074/jbc.ra118.006672
• Zhuo, C., Rao, X., Azad, R.K., Pandey, R., Xiao, X., Harkelroad, A., Wang, X., Chen, F., Dixon, R. (2019). Enzymatic basis for C-lignin monomer biosynthesis in the seed coat of Cleome hassleriana.. The Plant journal : for cell and molecular biology. 99 506-520.
• He, Y., Zhou, L., Gao, S., Yin, T., Tu, Y., Wang, X., Rayford, R., Hu, M. (2018). Development and validation of a sensitive LC-MS/MS method for simultaneous determination of eight tyrosine kinase inhibitors and its application in mice pharmacokinetic studies. Journal of Pharmaceutical and Biomedical Analysis. 148 65-72.
• Pan, Z., Baerson, S.R., Wang, M., Bajsa-Hirschel, J., Rimando, A.M., Wang, X., Nanayakkara, N.P., Noonan, B.P., Fromm, M.E., Dayan, F.E., Khan, I., Duke, S.O. (2018). Sorghum cytochrome P450 CYP71AM1 catalyzes the conversion of pentadecatrienyl resorcinol to dihydrosorgoleone in sorgoleone biosynthesis. New Phytologist. 218 616-629.
• Docampo, M., Olubu, A., Wang, X., Pasinetti, G., Dixon, R. (2017). Glucuronidated flavonoids in neurological protection: structural analysis and approaches for chemical and biological synthesis. Journal of Agricultural and Food Chemistry. 65 7607-7623.
• Liu, C., Wang, X., Shulaev, V., Dixon, R. (2016). A role for leucoanthocyanidin reductase in the extension of proanthocyanidins.. Nature Plants. 2 16182.
• Wu, X., Wu, F.H., Wang, X., Wang, L., Siedow, J.N., Zhang, W., Pei, Z.M.. (2014).
• Pan, H., Zhou, R., Louie, G.V., Mühlemann, J.K., Bomati, E.K., Bowman, M.E., Dudareva, N., Dixon, R.A., Noel, J.P., Wang, X.. (2014).
• Zhao, Q., Nakashima, J., Chen, F., Yin, Y., Fu, C., Yun, J., Shao, H., Wang, X., Wang, Z., Dixon, R.. (2013).
• Wu, B., Wang, X., Zhang, S., Hu, M.. (2012).
• Wu, B., Basu, S., Meng, S., Wang, X., Hu, M.. (2011).
• Li, L., Cheng, N., Hirschi, K.D., Wang, X.. (2010).
• Modolo, L.V., Escamilla-Trevino L.L., Dixon, R.A., Wang, X.. (2009).
• Modolo, L.V., Li, L., Pan, H., Blount, J.W., Dixon, R.A., Wang, X.. (2009).
• Wang, X.. (2009).
• Li, L., Chang, Z., Pan, Z., Fu, Z., Wang, X.. (2008).
• Shao, H., Dixon, R.A., Wang, X.. (2007).
• Li, L., Modolo, L.V., Escamilla-Trevino L.L., Achnine, L., Dixon, R.A., Wang, X.. (2007).
• Modolo, L.V., Blount, J.W., Achnine, L., Naoumkina, M.A., Wang, X., Dixon, R.A.. (2007).
• He, X., Wang, X., Dixon, R.A.. (2006).
• Wang, X., He, X., Lin, J., Shao, H., Chang, Z., Dixon, R.A.. (2006).
• Shao, H., He, X., Achnine, L., Blount, J.W., Dixon, R.A., Wang, X.. (2005).
• Wang, X., McLachlan, J., Zamore, P.D., Hall, T.M.T.. (2002). Modular recognition of RNA by a human Pumilio-homology domain. Cell. 110 501-512.
• Wang, X., Zamore, P.D., Hall, T.M.T.. (2001). Crystal structure of a Pumilio homology domain. Molecular Cell. 7 855-865.
• Wang, X., Hall, T.M.T.. (2001). Structural basis for recognition of AU-rich element RNA by the HuD protein. Nature Structural Biology. 8 141-145.
• Wang, X., Lin, X., Loy, J.A., Tang, J., Zhang, X.C.. (1998).
• Wang, X., Wang, C., Tang, J., Dyda, F., Zhang, X.C.. (1997).
• Wang, X., Yang, J., Gui, L., Lin, Z., Chen, Y., Zhou, Y.. (1996).
• Xie, C., Wang, X., Song, Z., Qu, S., Wang, P., Quo, Z.. (1992).
• Wang, X., Xie, C., Qu, S., Zhou, Z.. (1991).

Contracts, Grants and Sponsored Research

Contract

• Wang, X. (Principal), "Enzyme design and engineering toward synthesis of bioactive products," sponsored by Conagen Inc, Private, $242502 Funded. (2018 - 2026).
• Wang, X. (Principal), "Development of drug detoxifying bacteria for chemotherapy induced gut injury," sponsored by NIH, Federal, $140000 Funded. (2021 - 2023).
• Wang, X. (Principal), "Enzyme design and engineering toward synthesis of bioactive products," sponsored by Conagen Inc, Private, Funded. (2018 - 2022).

Grant - Research

• Skellam, E.J., Wang, X., "Molecular and structural studies of the first fungal polyketide synthase / non-ribosomal peptide synthetase adenylation domain toward biomolecular probes design," sponsored by UNT BDI, University of North Texas, $10000 Funded. (2022).
• Wang, X. (Principal), Nakata, P. (Co-Principal), "Structural and mechanistic studies of oxalate catabolism," sponsored by NSF, Federal, $800000 Funded. (2023 - 2026).
• Chapman, K.D. (Principal), Wang, X. (Supporting), "Molecular targets and actions of ethanolamide oxylipins in Arabidopsis thaliana," sponsored by NSF Integrative Organismal Systems (IOS 1656263), Federal, $796365 Funded. (2017 - 2021).
• Wang, X. (Principal), "UGT engineering for detoxifying anticancer drug SN-38," sponsored by NIH/NCI, Federal, $451570 Funded. (2015 - 2019).
• Chan, T. (Supporting), Wang, X. (Principal), "Development of Drug Detoxifying Bacteria for Chemotherapy Induced Gut Injury," sponsored by Sanarentero LLC, IND, Funded. (2021 - 2022).
• Chapman, K.D. (Principal), "Molecular Targets and Actions of Ethanolamide-Conjugated Oxylipins in Arabidopsis Thaliana," sponsored by National Science Foundation, FED, Funded. (2017 - 2021).
• Longo, A. (Co-Principal), Wang, X. (Principal), "UGT Engineering for Detoxifying Anticancer Drug SN-38," sponsored by National Institutes of Health, FED, Funded. (2015 - 2019).

Grant - Service

• Wang, X. (Principal), "Engineering glycosylation toward discovery of novel products and drugs," sponsored by UNT's I-GRO fund - Global Discovery Program, University of North Texas, $6000 Funded. (2014 - 2015).