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Youngwook Won

Title: Associate Professor

Department: Biomedical Engineering

College: College of Engineering

Curriculum Vitae

Curriculum Vitae Link

Education

  • PhD, Hanyang University - South Korea, 2011
    Major: Bioengineering

Current Scheduled Teaching

BMEN 5326.001Biomolecular EngineeringSpring 2026
BMEN 6910.014Individual ResearchSpring 2026
BMEN 4326.001Principles of Biomolecular EngineeringSpring 2026 Syllabus
BMEN 5900.012Special Problems in Biomedical EngineeringSpring 2026

Previous Scheduled Teaching

BMEN 5327.001Immuno engineeringFall 2025 SPOT
BMEN 6910.017Individual ResearchFall 2025
BMEN 5900.016Special Problems in Biomedical EngineeringFall 2025
BMEN 5900.016Special Problems in Biomedical EngineeringSummer 10W 2025
BMEN 5326.001Biomolecular EngineeringSpring 2025 SPOT
BMEN 5326.601Biomolecular EngineeringSpring 2025 SPOT
BMEN 6910.014Individual ResearchSpring 2025
BMEN 6910.022Individual ResearchSpring 2025
BMEN 4326.001Principles of Biomolecular EngineeringSpring 2025 Syllabus SPOT
BMEN 5900.012Special Problems in Biomedical EngineeringSpring 2025
BMEN 6950.015Biomedical Engineering Doctoral DissertationFall 2024
BMEN 5327.001Immuno engineeringFall 2024 SPOT
BMEN 5900.016Special Problems in Biomedical EngineeringFall 2024
BMEN 5900.017Special Problems in Biomedical EngineeringFall 8W2 2024
BMEN 6910.001Individual ResearchSummer 10W 2024
BMEN 5900.016Special Problems in Biomedical EngineeringSummer 10W 2024
BMEN 5326.001Biomolecular EngineeringSpring 2024 SPOT
BMEN 5326.601Biomolecular EngineeringSpring 2024 SPOT
BMEN 6910.014Individual ResearchSpring 2024
BMEN 4326.001Principles of Biomolecular EngineeringSpring 2024 Syllabus SPOT
BMEN 5900.012Special Problems in Biomedical EngineeringSpring 2024
BMEN 5327.001Immuno engineeringFall 2023 SPOT
BMEN 5900.016Special Problems in Biomedical EngineeringSummer 10W 2023
BMEN 5326.001Biomolecular EngineeringSpring 2023 SPOT
BMEN 5326.601Biomolecular EngineeringSpring 2023 SPOT
BMEN 4326.001Principles of Biomolecular EngineeringSpring 2023 Syllabus SPOT
BMEN 5900.012Special Problems in Biomedical EngineeringSpring 2023
BMEN 5810.001Topics in Biomedical EngineeringFall 2022 SPOT

Published Intellectual Contributions

    Journal Article

  • , , Han, S., , , , , , Won, Y. (2025). CliCAR: A non-genetic CAR engineering strategy to empower NK cells for targeted cancer immunotherapy.
  • Lim, S.Y., Kim, Y., Han, S., Kim, H., Ha, S., Park, J., Yun, J., Chae, S., Won, Y., Lim, K.S. (2025). CliCAR: A non-genetic CAR engineering strategy to empower NK cells for targeted cancer immunotherapy. Other. 193 118691. Elsevier BV. https://doi.org/10.1016/j.biopha.2025.118691
  • Kim, Y., Kwak, J., Lim, M., Lim, S.Y., Chae, S., Ha, S., Won, Y., Kim, H., Lim, K.S. (2025). Advances in PCL, PLA, and PLGA-Based Technologies for Anticancer Drug Delivery. Other. 17 (10) 1354. MDPI AG. https://doi.org/10.3390/pharmaceutics17101354
  • , , , , , , Won, Y. (2025). Advances in PCL, PLA, and PLGA-Based Technologies for Anticancer Drug Delivery. Pharmaceutics.
  • Lim, S.Y., Kim, Y., Kim, H., Han, S., Yun, J., Kim, H., Ha, S., Chae, S., Won, Y., Lim, K.S. (2025). Surface Engineering of Natural Killer Cells with Lipid-Based Antibody Capture Platform for Targeted Chemoimmunotherapy. Other. 17 (10) 1285. MDPI AG. https://doi.org/10.3390/pharmaceutics17101285
  • , , , , , , , , Won, Y. (2025). Surface Engineering of Natural Killer Cells with Lipid-Based Antibody Capture Platform for Targeted Chemoimmunotherapy.
  • , , , , , , , , Won, Y. (2025). Advanced breast cancer immunotherapy: Surface modification of NK cells for embedding antibody-drug conjugates.
  • Lim, S.Y., Han, S., Kim, Y., Kim, H., Kim, Y., Park, J., Yun, J., Yong, S., Won, Y., Lim, K.S. (2025). Advanced breast cancer immunotherapy: Surface modification of NK cells for embedding antibody-drug conjugates. Other. 189 118245. Elsevier BV. https://doi.org/10.1016/j.biopha.2025.118245
  • Kim, Y., Lim, S.Y., Kim, H., Ha, S., Park, J., Won, Y., Chae, S., Lim, K.S. (2025). Combination Strategies with HSP90 Inhibitors in Cancer Therapy: Mechanisms, Challenges, and Future Perspectives. Other. 18 (8) 1083. MDPI AG. https://doi.org/10.3390/ph18081083
  • Choi, S.H., Mani, M., Kim, J., Cho, W.J., Martin, T.F., Kim, J.H., Chu, H.S., Jeong, W.J., Won, Y., Lee, B.J., Ahn, B., Kim, J., Jeon, D.Y., Park, J.W. (2024). DRG2 is required for surface localization of PD-L1 and the efficacy of anti-PD-1 therapy. Other. 10 (1) Springer Science and Business Media LLC. https://doi.org/10.1038/s41420-024-02027-x
  • , , , , Won, Y. (2024). Hedgehog signalling is involved in acquired resistance to KRASG12C inhibitors in lung cancer cells.
  • Lee, C., Yi, J., Park, J., Ahn, B., Won, Y., Jeon, J., Lee, B.J., Cho, W.J., Park, J.W. (2024). Hedgehog signalling is involved in acquired resistance to KRASG12C inhibitors in lung cancer cells. Other. 15 (1) Springer Science and Business Media LLC. https://doi.org/10.1038/s41419-024-06436-9
  • , , , , , , , , Won, Y. (2023). DRG2 in macrophages is crucial for initial inflammatory response and protection against Listeria monocytogenes infection.
  • Lee, U.H., Park, S.J., Ju, S.A., Lee, S.C., Kim, B.S., Ahn, B., Yi, J., Park, J., Won, Y., Han, I.S., Lee, B.J., Cho, W.J., Park, J.W. (2023). DRG2 in macrophages is crucial for initial inflammatory response and protection against Listeria monocytogenes infection. Other. 257 109819. Elsevier BV. https://doi.org/10.1016/j.clim.2023.109819
  • Han, S., Lim, K.S., Blackburn, B.J., Yun, J., Putnam, C.W., Bull, D.A., Won, Y. (2022). The Potential of Topoisomerase Inhibitor-Based Antibody–Drug Conjugates. Other. 14 (8) 1707. MDPI AG. https://doi.org/10.3390/pharmaceutics14081707
  • Zenhausern, R., Day, A.S., Safavinia, B., Han, S., Rudy, P.E., Won, Y., Yoon, J. (2022). Natural killer cell detection, quantification, and subpopulation identification on paper microfluidic cell chromatography using smartphone-based machine learning classification. Other. 200 113916. Elsevier BV. https://doi.org/10.1016/j.bios.2021.113916
  • Khandelwal Gilman, K.A., Han, S., Won, Y., Putnam, C.W. (2021). Complex interactions of lovastatin with 10 chemotherapeutic drugs: a rigorous evaluation of synergism and antagonism. BMC Cancer. 21 (1) Springer Science and Business Media LLC. https://doi.org/10.1186/s12885-021-07963-w
  • Lim, K.S., Lee, D.Y., Han, S., Bull, D.A., Won, Y. (2021). Targeted delivery of heat shock protein 90 inhibitors prevents growth of HER2-positive tumor. Biomaterials. 273 120817. Elsevier BV. https://doi.org/10.1016/j.biomaterials.2021.120817
  • , , , , Won, Y. (2021). Targeted delivery of heat shock protein 90 inhibitors prevents growth of HER2-positive tumor.
  • Won, Y., Ankoné, M., Engbersen, J.F., Feijen, J., Kim, S.W. (2016). Poly(Amido Amine)s Containing Agmatine and Butanol Side Chains as Efficient Gene Carriers. Other. 16 (4) 619-626. Wiley. https://doi.org/10.1002/mabi.201500369
  • Won, Y., Bull, D.A., Kim, S.W. (2014). Functional polymers of gene delivery for treatment of myocardial infarct. Other. 195 110-119. Elsevier BV. https://doi.org/10.1016/j.jconrel.2014.07.041
  • Won, Y., Adhikary, P.P., Lim, K.S., Kim, H.J., Kim, J.K., Kim, Y. (2014). Oligopeptide complex for targeted non-viral gene delivery to adipocytes. Nature Materials. 13 (12) 1157-1164. Springer Science and Business Media LLC. https://doi.org/10.1038/nmat4092
  • Won, Y., Patel, A.N., Bull, D.A. (2014). Cell surface engineering to enhance mesenchymal stem cell migration toward an SDF-1 gradient. Biomaterials. 35 (21) 5627-5635. Elsevier BV. https://doi.org/10.1016/j.biomaterials.2014.03.070
  • Won, Y., Yoon, S., Lim, K.S., Kim, Y. (2012). Self‐Assembled Nanoparticles with Dual Effects of Passive Tumor Targeting and Cancer‐Selective Anticancer Effects. Advanced Functional Materials. 22 (6) 1199-1208. Wiley. https://doi.org/10.1002/adfm.201101979
  • Won, Y., Kim, K., An, S.S., Lee, M., Ha, Y., Kim, Y. (2011). Suicide gene therapy using reducible poly (oligo-d-arginine) for the treatment of spinal cord tumors. Biomaterials. 32 (36) 9766-9775. Elsevier BV. https://doi.org/10.1016/j.biomaterials.2011.08.089
  • Won, Y., Kim, Y. (2008). Recombinant human gelatin nanoparticles as a protein drug carrier. Other. 127 (2) 154-161. Elsevier BV. https://doi.org/10.1016/j.jconrel.2008.01.010

Contracts, Grants and Sponsored Research

    Grant - Research

  • Won, Y. (Principal), "Feasibility test of an injectable form of immune modulator," sponsored by Thunder Bay Therapeutics, Private, $250000 Funded. (2024 - 2026).
  • Won, Y. (Principal), "Feasibility test of an injectable form of immune modulator," sponsored by Thunder Bay Therapeutics, Private, $200000 Funded. (2023 - 2024).
  • Won, Y. (Principal), "Targeted Systemic Delivery of SDF-1 DNA for the Treatment of Chronic Heart Disease," sponsored by NIH, Federal, $41831 Funded. (2023 - 2024).
  • Won, Y. (Principal), "Feasibility test of an injectable form of immune modulator," sponsored by Thunder Bay Therapeutics, Private, $100000 Funded. (2022 - 2023).
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Overall
Summative Rating
Challenge and
Engagement Index
Response Rate

out of 5

out of 7
%
of
students responded
  • Overall Summative Rating (median):
    This rating represents the combined responses of students to the four global summative items and is presented to provide an overall index of the class’s quality. Overall summative statements include the following (response options include a Likert scale ranging from 5 = Excellent, 3 = Good, and 1= Very poor):
    • The course as a whole was
    • The course content was
    • The instructor’s contribution to the course was
    • The instructor’s effectiveness in teaching the subject matter was
  • Challenge and Engagement Index:
    This rating combines student responses to several SPOT items relating to how academically challenging students found the course to be and how engaged they were. Challenge and Engagement Index items include the following (response options include a Likert scale ranging from 7 = Much higher, 4 = Average, and 1 = Much lower):
    • Do you expect your grade in this course to be
    • The intellectual challenge presented was
    • The amount of effort you put into this course was
    • The amount of effort to succeed in this course was
    • Your involvement in course (doing assignments, attending classes, etc.) was
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