LeGrande M. Slaughter

Previous Scheduled Teaching

Published Intellectual Contributions

Book

• Slaughter, L.M. (2015). Homogeneous Gold Catalysis. Topics in Current Chemistry, Vol. 357. Heidelberg, Springer.

Book Chapter

• Slaughter, L.M., Nolan, S.P. (2014). Catalysis with Acyclic Aminocarbene Ligands: Alternatives to NHCs with Distinct Steric and Electronic Properties. Other. N-Heterocyclic Carbenes: Effective Tools for Organometallic Synthesis. 499–524. Weinheim, Wiley-VCH Verlag GmbH & Co. KGaA.

Journal Article

• Ruch, A., Ellison, M.C., Nguyen, J.K., Kong, F., Handa, S., Nesterov, V.N., Slaughter, L.M. (2021). Highly Sterically Encumbered Gold Acyclic Diaminocarbene Complexes: Overriding Electronic Control in Regiodivergent Gold Catalysis. Organometallics. 40 1416-1433. https://pubs.acs.org/doi/pdf/10.1021/acs.organomet.0c00776
• Majek, P., Krupcik, J., Breitbach, Z.S., Dissanayake, M.K., Kroll, P., Ruch, A.A., Slaughter, L.M., Armstrong, D.W. (2017). Determination of the interconversion energy barrier of three novel pentahelicene derivative enantiomers by dynamic high resolution liquid chromatography. Journal of Chromatography B. 1051 60–67. Elsevier. https://www.sciencedirect.com/science/article/pii/S1570023216314568?pes=vor
• Ruch, A.A., Handa, S., Kong, F., Nesterov, V.N., Pahls, D.R., Cundari, T.R., Slaughter, L.M. (2016). Competing amination and C-H arylation pathways in Pd/xantphos-catalyzed transformations of binaphthyl triflates: switchable routes to chiral amines and helicene derivatives. Organic & Biomolecular Chemistry. 14 (34) 8123-8140. THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND, ROYAL SOC CHEMISTRY.
• Ruch, A.A., Kong, F., Nesterov, V.N., Slaughter, L.M. (2016). Tetracyclic dihydronaphthalene derivatives via gold-catalyzed aminative homodimerization of ortho-alkynylbenzaldehydes. Chemical Communications. 52 (98) 14133–14136. Royal Society of Chemistry. https://pubs.rsc.org/en/content/articlelanding/2016/CC/C6CC08132K
• Handa, S., Subramanium, S.S., Ruch, A.A., Tanski, J.M., Slaughter, L.M. (2015). Ligand-and Brønsted acid/base-switchable reaction pathways in gold (I)-catalyzed cycloisomerizations of allenoic acids. Organic & Biomolecular Chemistry. 13 (13) 3936–3949. Royal Society of Chemistry.
• Prema, D., Mathota Arachchige, Y.L., Murray, R.E., Slaughter, L.M. (2015). “Decarbonization” of an imino-N-heterocyclic carbene ligand via triple benzyl migration from hafnium. Chemical Communications. 51 (31) 6753–6756. Royal Society of Chemistry.
• Handa, S., Mathota Arachchige, Y.L., Slaughter, L.M. (2013). Access to 2'-Substituted Binaphthyl Monoalcohols via Complementary Nickel-Catalyzed Kumada Coupling Reactions under Mild Conditions: Key Role of a P, O Ligand. Journal of Organic Chemistry. 78 (11) 5694–5699. ACS Publications.
• Nanayakkara, Y.S., Woods, R.M., Breitbach, Z.S., Handa, S., Slaughter, L.M., Armstrong, D.W. (2013). Enantiomeric separation of isochromene derivatives by high-performance liquid chromatography using cyclodextrin based stationary phases and principal component analysis of the separation data. Journal of Chromatography A. 1305 94–101. Elsevier.
• Slaughter, L.M. (2012). Acyclic aminocarbenes in catalysis. ACS Catalysis. 2 (8) 1802–1816. American Chemical Society.
• Owusu, M.O., Handa, S., Slaughter, L.M. (2012). Chugaev-type bis (acyclic diaminocarbenes) as a new ligand class for the palladium-catalyzed Mizoroki–Heck reaction. Applied Organometallic Chemistry. 26 (12) 712-717.
• Handa, S., Slaughter, L.M. (2012). Enantioselective alkynylbenzaldehyde cyclizations catalyzed by chiral gold (I) acyclic diaminocarbene complexes containing weak Au–arene interactions. Angewandte Chemie International Edition. 124 (12) 2966–2969. Wiley Online Library.
• Sluch, I.M., Miranda, A.J., Elbjeirami, O., Omary, M.A., Slaughter, L.M. (2012). Interplay of metallophilic interactions, $\pi$--$\pi$ stacking, and ligand substituent effects in the structures and luminescence properties of neutral PtII and PdII aryl isocyanide complexes. Inorganic Chemistry. 51 (20) 10728--10746. American Chemical Society.
• Sluch, I.M., Miranda, A.J., Elbjeirami, O., Omary, M.A., Slaughter, L.M. (2012). Interplay of Metallophilic Interactions, π–π Stacking, and Ligand Substituent Effects in the Structures and Luminescence Properties of Neutral PtII and PdII Aryl Isocyanide Complexes. Inorganic Chemistry. 51 (20) 10728–10746. ACS Publications.
• Singh, P., Raj, R., Bhargava, G., Hendricks, D.T., Handa, S., Slaughter, L.M., Kumar, V. (2012). β-Lactam synthon-interceded diastereoselective synthesis of functionalized octahydroindole-based molecular scaffolds and their in vitro cytotoxic evaluation. European Journal of Medicinal Chemistry. 58 513–518. Elsevier.
• Subramanium, S.S., Handa, S., Miranda, A.J., Slaughter, L.M. (2011). Simple silver salts and palladium bis (N-heterocyclic carbene) complexes as complementary catalysts for the Nazarov cyclization. ACS Catalysis. 1 (10) 1371–1374. American Chemical Society.
• Raj, R., Mehra, V., Singh, P., Kumar, V., Bhargava, G., Mahajan, M.P., Handa, S., Slaughter, L.M. (2011). β-Lactam-synthon-interceded, facile, one-pot, diastereoselective synthesis of functionalized tetra/octahydroisoquinolone derivatives. European Journal of Organic Chemistry. 2011 (14) 2697–2704. Wiley Online Library.
• Sluch, I.M., Miranda, A.J., Slaughter, L.M. (2009). Channeled polymorphs of cis-M(CNPh)2Cl2 (M= Pt, Pd) with extended metallophilic interactions. Crystal Growth & Design. 9 (3) 1267–1270. ACS Publications.
• Subramanium, S.S., Slaughter, L.M. (2009). Direct observation of a carbonylation reaction relevant to CO/alkene copolymerization in a methylpalladium carbonyl complex containing a bis (N-heterocyclic carbene) ligand. Dalton Transactions. (35) 6930–6933. Royal Society of Chemistry.
• Bunce, R.A., Nammalwar, B., Slaughter, L.M. (2009). Divergent reactivity in tandem reduction–Michael ring closures of five-and six-membered cyclic enones. Journal of Heterocyclic Chemistry. 46 (5) 854–860. John Wiley & Sons, Inc..
• Wanniarachchi, Y.A., Subramanium, S.S., Slaughter, L.M. (2009). Palladium complexes of bis (acyclic diaminocarbene) ligands with chiral N-substituents and 8-membered chelate rings. Journal of Organometallic Chemistry. 694 (20) 3297–3305. Elsevier.
• Slaughter, L.M. (2008). "Covalent self-assembly" of acyclic diaminocarbene ligands at metal centers. Comments on Inorganic Chemistry. 29 (1-2) 46–72. Taylor & Francis Group.
• Bunce, R.A., Nago, T., Sonobe, N., Slaughter, L.M. (2008). Benzo-fused heterocycles and carbocycles by intramolecular SNAr and tandem SN2-SNAr reactions. Journal of Heterocyclic Chemistry. 45 (2) 551–557. HeteroCorporation.
• Wanniarachchi, Y.A., Kogiso, Y., Slaughter, L.M. (2008). Chiral palladium bis (acyclic diaminocarbene) complexes as enantioselective catalysts for the aza-Claisen rearrangement. Organometallics. 27 (1) 21–24. American Chemical Society.
• Al-Far, A.M., Slaughter, L.M. (2008). cis-cis-trans-Bis (acetonitrile-κN) dichloridobis (triphenylphosphine-κP) ruthenium (II) acetonitrile disolvate. Acta Crystallographica. 64 (1) m184–m184. International Union of Crystallography.
• Wanniarachchi, Y.A., Slaughter, L.M. (2008). Reversible chelate ring opening of a sterically crowded palladium bis (acyclic diaminocarbene) complex. Organometallics. 27 (6) 1055–1062. American Chemical Society.
• Bunce, R.A., Schammerhorn, J.E., Slaughter, L.M. (2007). (±)-2, 3-Dialkyl-1, 2, 3, 4-tetrahydroquinoline-3-carboxylic esters by a tandem reduction-reductive amination reaction. Journal of Heterocyclic Chemistry. 44 (5) 1051–1057. Wiley-Blackwell.
• Wanniarachchi, Y.A., Slaughter, L.M. (2007). One-step assembly of a chiral palladium bis (acyclic diaminocarbene) complex and its unexpected oxidation to a bis (amidine) complex. Chemical Communications. (31) 3294–3296. Royal Society of Chemistry.
• Sluch, I.M., Slaughter, L.M. (2007). trans-Diaquadichloridobis (N, N-dimethylformamide-κO) manganese (II). Acta Crystallographica. 63 (12) m3095–m3095. International Union of Crystallography.
• Bunce, R.A., Schammerhorn, J.E., Slaughter, L.M. (2006). Catalyst and pressure dependent reductive cyclizations for the diastereo-selective synthesis of hexahydropyrrolo [1, 2-a] quinoline-5-carboxylic esters. Journal of Heterocyclic Chemistry. 43 (6) 1505–1511. Wiley-Blackwell.
• Moncada, A.I., Manne, S., Tanski, J.M., Slaughter, L.M. (2006). Modular Chelated Palladium Diaminocarbene Complexes: Synthesis, Characterization, and Optimization of Catalytic Suzuki- Miyaura Cross-Coupling Activity by Ligand Modification. Organometallics. 25 (2) 491–505. American Chemical Society.
• Moncada, A.I., Khan, M.A., Slaughter, L.M. (2005). A palladium Chugaev carbene complex as a modular, air-stable catalyst for Suzuki–Miyaura cross-coupling reactions. Other. 46 (9) 1399–1403. Elsevier.
• Moncada, A.I., Tanski, J.M., Slaughter, L.M. (2005). Sterically controlled formation of monodentate versus chelating carbene ligands from phenylhydrazine. Journal of Organometallic Chemistry. 690 (24) 6247–6251. Elsevier.
• Wanniarachchi, Y.A., Khan, M.A., Slaughter, L.M. (2004). An unusually static, sterically hindered silver bis (N-heterocyclic carbene) complex and its use in transmetalation. Organometallics. 23 (25) 5881–5884. ACS Publications.
• Slaughter, L.M., Collman, J.P., Eberspacher, T.A., Brauman, J.I. (2004). Radical Autoxidation and Autogenous O2 Evolution in Manganese- Porphyrin Catalyzed Alkane Oxidations with Chlorite. Inorganic Chemistry. 43 (17) 5198–5204. American Chemical Society.
• Veige, A.S., Slaughter, L.M., Lobkovsky, E.B., Wolczanski, P.T., Matsunaga, N., Decker, S.A., Cundari, T.R. (2003). Symmetry and Geometry Considerations of Atom Transfer: Deoxygenation of (silox) 3WNO and R3PO (R= Me, Ph, tBu) by (silox) 3M (M= V, NbL (L= PMe3, 4-Picoline), Ta; silox= tBu3SiO). Inorganic Chemistry. 42 (20) 6204–6224. ACS Publications.
• Veige, A.S., Slaughter, L.M., Wolczanski, P.T., Matsunaga, N., Decker, S.A., Cundari, T.R. (2001). Deoxygenations of (silox)3WNO and R3PO by (silox)3M (M = V, Ta) and (silox)3NbL (silox = tBu3SiO): Consequences of Electronic Effects. Journal of the American Chemical Society. 123 (26) 6419–6420. American Chemical Society.
• Collman, J.P., Slaughter, L.M., Eberspacher, T.A., Strassner, T., Brauman, J.I. (2001). Mechanism of dihydrogen cleavage by high-valent metal oxo compounds: Experimental and computational studies. Inorganic Chemistry. 40 (24) 6272–6280. ACS Publications.
• Slaughter, L.M., Wolczanski, P.T., Klinckman, T.R., Cundari, T.R. (2000). Inter-and Intramolecular Experimental and Calculated Equilibrium Isotope Effects for (silox) 2 (tBu3SiND) TiR+ RH (silox= tBu3SiO): Inferred Kinetic Isotope Effects for RH/D Addition to Transient (silox) 2Ti=NSitBu3. Journal of the American Chemical Society. 122 (33) 7953–7975. ACS Publications.
• Slaughter, L.M., Wolczanski, P.T. (1997). Ti(μ:η1,η1-OCMe2CH2PPh2)3Rh has a cylindrically symmetric triple bond. Chemical Communications. 1997 (21) 2109–2110. Royal Society of Chemistry.

Contracts, Grants and Sponsored Research

Grant - Research

• Slaughter, L.M. (Principal), Wang, H. (Co-Principal), "REU Site: Team-Mentored Interdisciplinary Research Experiences in Chemistry for Early-Stage Undergraduates," sponsored by National Science Foundation, Federal, $279576 Funded. (2018 - 2023).
• Slaughter, L.M. (Principal), "Earth-Abundant Metal Catalysts for Conversion of Seed Oils to Drop-In Fuels," sponsored by UNT Division of Research & Innovation, University of North Texas, $10000 Funded. (2022 - 2023).
• Slaughter, L.M. (Principal), Chapman, K.D. (Co-Principal), "Upgrading Plant-Based Biofuels via Metal-Catalyzed Decarboxylation," sponsored by UNT College of Science Collaborative Seed Grant, University of North Texas, $9000 Funded. (2020 - 2020).
• Slaughter, L.M., D'Souza, F., Omary, M.A., Richmond, M.G., Wang, H., "MRI: Acquisition of a Microfocus X-Ray Diffractometer as a Regionwide Resource for Chemistry and Materials Research," sponsored by National Science Foundation, Federal, $262689 Funded. (2017 - 2020).
• Omary, M.A. (Principal), Slaughter, L.M. (Co-Principal), Du, J. (Co-Principal), "Mesoscale Integrated Temporally-Triggered Heterostructures with Remote Indicating Luminescence (MITHRIL)," sponsored by Intelligence Advanced Research Projects Agency (IARPA), subcontract via Leidos, Inc., Federal, $304717 Funded. (2018 - 2019).
• Slaughter, L.M. (Principal), "REU Site: Undergraduate Research Opportunities at the Interface of Computational and Experimental Chemistry at the University of North Texas," sponsored by National Science Foundation, Federal, $243742 Funded. (2015 - 2019).
• SLAUGHTER, L.M. (Principal), Omary, M.A. (Co-Principal), Shi, S.Q. (Co-Principal), "Designer Porous Framework Materials for Catalysis," sponsored by UNT Advanced Materials & Manufacturing Processes Institute (AMMPI) Seed Grant, University of North Texas, $15000 Funded. (2018 - 2018).
• Cundari, T.R. (Principal), Borden, W.T. (Co-Principal), Bagus, P.S. (Co-Principal), Marshall, P. (Co-Principal), Buongiorno Nardelli, M. (Co-Principal), Slaughter, L.M. (Supporting), "MRI: Acquisition of a Computer Cluster for the Computational Chemistry Program at the University of North Texas," sponsored by National Science Foundation, Federal, $400000 Funded. (2015 - 2018).
• Slaughter, L.M. (Principal), "Harnessing Nonclassical Metal-Arene Interactions to Achieve Enantioselective Catalysis," sponsored by National Science Foundation, Federal, $405000 Funded. (2012 - 2017).
• Slaughter, L.M. (Principal), Wilson, A.K. (Co-Principal), Cundari, T.R. (Co-Principal), Omary, M.A. (Co-Principal), "Bonding Analysis Workshop in Marburg, Germany," sponsored by UNT Incentives for Global Research Opportunities (I-GRO), Global Discovery Program, University of North Texas, $8300 Funded. (2015 - 2015).
• Slaughter, L.M. (Supporting), Frenking, G. (Principal), "Establishing Cooperation in Computational/Theoretical Chemistry Between Research Groups in Marburg and the University of North Texas," sponsored by Deutsche Forschungsgemeinschaft (German Research Foundation), International, $8600 Funded. (2015 - 2015).
• Slaughter, L.M. (Principal), "Supplement to Existing Single-PI Award for Initiation of International Research Activities," sponsored by National Science Foundation, Federal, $7548 Funded. (2014 - 2015).
• Slaughter, L.M. (Principal), "Novel Heterocycles Via Ligand-Tunable Gold Catalysis," sponsored by Oklahoma Center for the Advancement of Science & Technology, State, $90000 Funded. (2012 - 2014).
• Slaughter, L.M. (Principal), "REU Supplement to Existing Single-PI Award," sponsored by National Science Foundation, Federal, $7948 Funded. (2013 - 2013).
• Slaughter, L.M. (Principal), "CAREER: Self-Assembly of Electrophilic Late Metal Catalysts and Catalyzing Careers in Research," sponsored by National Science Foundation, Federal, $560000 Funded. (2007 - 2012).
• Slaughter, L.M. (Principal), "Novel Chelate Ligands for Olefin Polymerization Catalysis," sponsored by Chevron Phillips Chemical Company, Private, $227400 Funded. (2007 - 2011).
• Slaughter, L.M. (Co-Principal), Benson, S.D. (Principal), Du, J. (Co-Principal), "Single Crystal X-Ray Diffraction Facility Support," sponsored by Oklahoma State University Core Facilities Support Fund, Local, $51000 Funded. (2008 - 2008).
• Slaughter, L.M. (Principal), "Catalysis With Readily Modified Chelating Carbene Complexes," sponsored by American Chemical Society Petroleum Research Fund, Private, $35000 Funded. (2003 - 2005).
• Slaughter, L.M. (Principal), "Nanostructured Metal-Carbene Catalysts," sponsored by Oklahoma NSF EPSCoR NanoNet, State, $42145 Funded. (2004 - 2005).
• Slaughter, L.M. (Principal), "Efficient Catalysts for Bond Formation," sponsored by Oklahoma State University Environmental Institute Energy Center, Local, $9333 Funded. (2003 - 2004).
• Wang, H. (Co-Principal), Slaughter, L.M. (Principal), "REU Site: Team-Mentored Interdisciplinary Research Experiences in Chemistry for Early-Stage Undergraduates," sponsored by National Science Foundation, FED, Funded. (2018 - 2022).
• Slaughter, L.M. (Principal), Wang, H. (Co-Principal), "REU Site: Team-Mentored Interdisciplinary Research Experiences in Chemistry for Early-Stage Undergraduates," sponsored by National Science Foundation, Federal, Funded. (2018 - 2021).
• Omary, M.A. (Principal), "Luminescent Metal-Metal Bonded Exiplexes of Closed Shell Coordination Compounds," sponsored by Robert A. Welch Foundation, FOND, Funded. (2015 - 2021).
• D'Souza, F. (Principal), Wang, H. (Co-Principal), Slaughter, L.M. (Principal), Richmond, M.G. (Co-Principal), Omary, M.A. (Co-Principal), "MRI: Acquisition of a Microfocus X-Ray Diffractometer as a Regionwide Resource for Chemistry and Materials Research," sponsored by National Science Foundation, FED, Funded. (2017 - 2020).
• Wilson, A.K. (Other), Slaughter, L.M. (Principal), Cundari, T.R. (Co-Principal), "Environmental and Energy Research at the Texas Center for Advanced Scientific Computing and Modeling (CASCaM)," sponsored by U.S. Department of Energy, FED, Funded. (2008 - 2020).
• Du, J. (Co-Principal), Slaughter, L.M. (Principal), "Ithildin: Metal-Inorganic Frameworks (MIFs) for Remediation and Sensing of TICs, CWAs and Explosives," sponsored by Leidos, IND, Funded. (2018 - 2019).
• Omary, M.A. (Principal), Slaughter, L.M. (Co-Principal), Du, J. (Co-Principal), "Mesoscale Integrated Temporally-Triggered Heterostructures with Remote Indicating Luminescence (MITHRIL)," sponsored by Intelligence Advanced Research Projects Agency (IARPA), subcontract via Leidos, Inc., Federal, Funded. (2018 - 2019).
• Slaughter, L. (Principal), "REU Site: Undergraduate Research Opportunities at the Interface of Computational and Experimental Chemistry at the University of North Texas," sponsored by National Science Foundation, Federal, Funded. (2015 - 2019).
• Wilson, A.K. (Other), Slaughter, L.M. (Principal), "REU Site: Undergraduate Research Opportunities at the Interface of Computational and Experimental Chemistry at the University of North Texas," sponsored by National Science Foundation, FED, Funded. (2015 - 2019).
• Cundari, T.R. (Principal), Borden, W.T. (Co-Principal), Bagus, P. (Co-Principal), Marshall, P. (Co-Principal), Buongiorno Nardelli, M. (Co-Principal), Slaughter, L. (Supporting), "MRI: Acquisition of a Computer Cluster for the Computational Chemistry Program at the University of North Texas," sponsored by National Science Foundation, Federal, Funded. (2015 - 2018).
• Slaughter, L.M. (Principal), "Harnessing Nonclassical Metal-Arene Interactions to Achieve Enantioselective Catalysis," sponsored by National Science Foundation, FED, Funded. (2013 - 2017).
• Slaughter, L. (Supporting), Frenking, G. (Principal), "Establishing Cooperation in Computational/Theoretical Chemistry Between Research Groups in Marburg and the University of North Texas," sponsored by Deutsche Forschungsgemeinschaft (German Research Foundation), International, Funded. (2015 - 2015).
• Slaughter, L. (Principal), "Supplement to Existing Single-PI Award for Initiation of International Research Activities," sponsored by National Science Foundation, Federal, Funded. (2014 - 2015).
• Slaughter, L. (Principal), "Novel Heterocycles Via Ligand-Tunable Gold Catalysis," sponsored by Oklahoma Center for the Advancement of Science & Technology, State, Funded. (2012 - 2014).
• Slaughter, L. (Principal), "REU Supplement to Existing Single-PI Award," sponsored by National Science Foundation, Federal, Funded. (2013 - 2013).
• Slaughter, L. (Principal), "CAREER: Self-Assembly of Electrophilic Late Metal Catalysts and Catalyzing Careers in Research," sponsored by National Science Foundation, Federal, Funded. (2007 - 2012).
• Slaughter, L. (Principal), "Novel Chelate Ligands for Olefin Polymerization Catalysis," sponsored by Chevron Phillips Chemical Company, Private, Funded. (2007 - 2011).
• Slaughter, L. (Principal), "Nanostructured Metal-Carbene Catalysts," sponsored by Oklahoma NSF EPSCoR NanoNet, State, Funded. (2004 - 2005).