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Jiang, X., Dimas, R. P., Chan, C. T., Morcos, F. (2021). Coevolutionary methods enable robust design of modular repressors by reestablishing intra-protein interactions. Nature Communications. 12, 5592. https://doi.org/10.1038/s41467-021-25851-6
Dimas, R. P., Jordan, B. R., Jiang, X., Martini, C., Glavy, J. S., Patterson, D. P., Morcos, F., Chan, T. (2019). Engineering DNA recognition and allosteric response properties of TetR family proteins by using a module-swapping strategy. Other. 47(16), 8913-8925. Oxford University Press (OUP). http://dx.doi.org/10.1093/nar/gkz666
Dimas, R. P., Jiang, X., Alberto de la Paz, J., Morcos, F., Chan, T. (2019). Engineering repressors with coevolutionary cues facilitates toggle switches with a master reset. Other. 47(10), 5449-5463. Oxford University Press (OUP). http://dx.doi.org/10.1093/nar/gkz280
Lee, J. W., Chan, T., Slomovic, S., Collins, J. J. (2018). Next-generation biocontainment systems for engineered organisms. Nature Chemical Biology. 14(6), 530-537. https://api.elsevier.com/content/abstract/scopus_id/85047020981
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Chan, T., Deng, W., Li, F., Demott, M. S., Babu, I. R., Begley, T. J., Dedon, P. C. (2015). Highly Predictive Reprogramming of tRNA Modifications Is Linked to Selective Expression of Codon-Biased Genes. Chemical Research in Toxicology. 28(5), 978-988. https://api.elsevier.com/content/abstract/scopus_id/84929408617
Dwyer, D. J., Belenky, P. A., Yang, J. H., Cody MacDonald,, Martell, J. D., Takahashi, N., Chan, T., Lobritz, M. A., Braff, D., Schwarz, E. G., Ye, J. D., Pati, M., Vercruysse, M., Ralifo, P. S., Allison, K. R., Khalil, A. S., Ting, A. Y., Walker, G. C., Collins, J. J. (2014). Antibiotics induce redox-related physi. Proceedings of the National Academy of Sciences of the United States of America. 111(20), . https://api.elsevier.com/content/abstract/scopus_id/84901059678
Mandal, D., Köhrer, C., Su, D., Babu, I. R., Chan, T., Liu, Y., Söll, D., Blum, P., Kuwahara, M., Dedon, P. C., Rajbhandary, U. L. (2014). Identification and codon reading properties of 5-cyanomethyl uridine, a new modified nucleoside found in the anticodon wobble position of mutant haloarchaeal isoleucine tRNAs. Other. 20(2), 177-188. https://api.elsevier.com/content/abstract/scopus_id/84892739139
Su, D., Chan, T., Gu, C., Lim, K. S., Chionh, Y. H., McBee, M. E., Russell, B. S., Babu, I. R., Begley, T. J., Dedon, P. C. (2014). Quantitative analysis of ribonucleoside modifications in tRNA by HPLC-coupled mass spectrometry. Other. 9(4), 828-841. https://api.elsevier.com/content/abstract/scopus_id/84897129376
Begley, U., Sosa, M. S., Avivar-Valderas, A., Patil, A., Endres, L., Estrada, Y., Chan, T., Su, D., Dedon, P. C., Aguirre-Ghiso, J. A., Begley, T. (2013). A human tRNA methyltransferase 9-like protein prevents tumour growth by regulating LIN9 and HIF1-α. Other. 5(3), 366-383. https://api.elsevier.com/content/abstract/scopus_id/84874750617
Patil, A., Dyavaiah, M., Joseph, F., Rooney, J. P., Chan, T., Dedon, P. C., Begley, T. J. (2012). Increased tRNA modification and gene-specific codon usage regulate cell cycle progression during the DNA damage response. Other. 11(19), 3656-3665. https://api.elsevier.com/content/abstract/scopus_id/84867259656
Chan, T., Pang, Y. L., Deng, W., Babu, I. R., Dyavaiah, M., Begley, T. J., Dedon, P. C. (2012). Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins. Nature Communications. 3, . https://api.elsevier.com/content/abstract/scopus_id/84864828979
Patil, A., Chan, T., Dyavaiah, M., Rooney, J. P., Dedon, P. C., Begley, T. J. (2012). Translational infidelity-induced protein stress results from a deficiency in Trm9-catalyzed tRNA modifications. Other. 9(7), 990-1001. https://api.elsevier.com/content/abstract/scopus_id/84865298780
Chan, T., Chionh, Y. H., Ho, C., Lim, K. S., Babu, I. R., Ang, E., Wenwei, L., Alonso, S., Dedon, P. C. (2011). Identification of N6,N6-dimethyladenosine in transfer RNA from Mycobacterium bovis bacille calmette-guérin. Molecules. 16(6), 5168-5181. https://api.elsevier.com/content/abstract/scopus_id/79959627017
Chan, T., Dyavaiah, M., DeMott, M. S., Taghizadeh, K., Dedon, P. C., Begley, T. J. (2010). A quantitative systems approach reveals dynamic control of tRNA modifications during cellular stress. Other. 6(12), 1-9. https://api.elsevier.com/content/abstract/scopus_id/78650683942
Fu, D., Brophy, J. A., Chan, T., Atmore, K. A., Begley, U., Paules, R. S., Dedon, P. C., Begley, T. J., Samson, L. D. (2010). Human AlkB homolog ABH8 is a tRNA methyltransferase required for wobble uridine modification and DNA damage survival. Molecular and Cellular Biology. 30(10), 2449-2459. https://api.elsevier.com/content/abstract/scopus_id/77951981033
Seyedsayamdost, M. R., Chan, T., Mugnaini, V., Stubbe, J., Bennati, M. (2007). PELDOR spectroscopy with DOPA-β2 and NH2Y-α2s: Distance measurements between residues involved in the radical propagation pathway of E. coli ribonucleotide reductase. Journal of the American Chemical Society. 129(51), 15748-15749. https://api.elsevier.com/content/abstract/scopus_id/37549042071
Seyedsayamdost, M. R., Xie, J., Chan, T., Schultz, P. G., Stubbe, J. (2007). Site-specific insertion of 3-aminotyrosine into subunit α2 of E. coli ribonucleotide reductase: Direct evidence for involvement of Y730 and Y731 in radical propagation. Journal of the American Chemical Society. 129(48), 15060-15071. https://api.elsevier.com/content/abstract/scopus_id/36849004028