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Xin Cui

Title: Associate Professor

Department: Chemistry

College: College of Science

Curriculum Vitae

Curriculum Vitae Link

Current Scheduled Teaching

CHEM 6950.755Doctoral DissertationSpring 2025
CHEM 6940.755Individual ResearchSpring 2025
CHEM 2370.003Organic Chemistry ISpring 2025 Syllabus
CHEM 2370.203Organic Chemistry ISpring 2025

Previous Scheduled Teaching

CHEM 6950.755Doctoral DissertationFall 2024
CHEM 6940.755Individual ResearchFall 2024

Published Intellectual Contributions

    Book Chapter

  • Xu, X., Cui, X. (2022). Ruthenium‐Catalyzed Asymmetric CH Functionalization. Handbook of CH‐Functionalization. https://onlinelibrary.wiley.com/doi/10.1002/9783527834242.chf0130
  • Cui, X., Zhang, X. (2016). C–C Bond Formation Using Carbenes. Science of Synthesis: Catalytic Transformations via C–H Activation series. 2 63. Thieme. https://www.thieme.de/en/thieme-chemistry/sos-catalytic-transformations-via-C-H-activations-84665.htm
  • Cui, X., Zhang, X. (2014). Asymmetric C–H Functionalization by Transition Metal-Catalyzed Carbene Transfer Reactions. Comprehensive Organic Synthesis 2nd Edition. 7 86. Elsevier. https://www.sciencedirect.com/science/article/abs/pii/B9780080977423007047
  • Zhang, X., Cui, X. (2014). Asymmetric C–H Functionalization by Transition Metal-Catalyzed Carbene Transfer Reactions. Comprehensive Organic Synthesis (Second Edition). 7 86. https://www.sciencedirect.com/science/article/abs/pii/B9780080977423007047?via%3Dihub
  • Cui, X., Zhang, X. (2013). Cobalt-Mediated Carbene Transfer Reactions. Contemporary Carbene Chemistry. (15) 491. John Wiley & Sons. https://www.wiley.com/en-us/Contemporary+Carbene+Chemistry-p-9781118237953
  • Cui, X., Zhang, X. (2012). Iron(III) meso-Tetraphenylporphine Chloride. e-EROS Encyclopedia of Reagents for Organic Synthesis. John Wiley & Sons. https://onlinelibrary.wiley.com/doi/abs/10.1002/047084289X.rn01388
  • Journal Article

  • Nirosh Udayanga, D., Le, N., Schwirian, E., Donnadieu, B., Nash, K., Collier, W., Webster, C., Cui, X. (2023). Synthesis of N-Fused Polycyclic Indole Derivatives via Ru(II)-Catalyzed C–H Bond Activation and Intramolecular Hydroarylation. Organic Letters. 25 (48) 8745. https://pubs.acs.org/doi/10.1021/acs.orglett.3c03757
  • Wamsley, M., Peng, W., Tan, W., Wathudura, P., Cui, X., Zou, S., Zhang, D. (2023). Total Luminescence Spectroscopy for Quantification of Temperature Effects on Photophysical Properties of Photoluminescent Materials. 3 (1) 10. https://pubs.acs.org/doi/10.1021/acsmeasuresciau.2c00047
  • Chaminda Lakmal, H., Istre, J., Qian, X., Zhou, H., Valle, H., Xu, X., Cui, X. (2022). Catalytic Amidomethylative [2+2+2] Cycloaddition of Formaldimine and Styrenes toward N-Heterocycles. 54 (09) 2165. https://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-1710-7256
  • Smith, L., Nirosh Udayanga, D., Qian, X., Adams, L., Sims, S., Nettles, C., Xu, X., Cui, X., Mlsna, D. (2022). Iron-Based Tandem Catalysis: From Petroleum toward Pharmaceutical Laboratories for Organic Undergraduate Students─Product Identification by TLC and 1H NMR. Journal of Chemical Education. 99 (9) 3259. https://pubs.acs.org/doi/10.1021/acs.jchemed.2c00451
  • Shayegan, M., Li, Z., Cui, X. (2022). Ligand-Controlled Regiodivergence for Catalytic Stereoselective Semireduction of Allenamides. Chemistry - A European Journal. 28 (1) e202103402. https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.202103402
  • Qian, X., Zhou, H., Chaminda Lakmal, H., Lucore, J., Wang, X., Valle, H., Donnadieu, B., Xu, X., Cui, X. (2021). Fe(III)-Based Tandem Catalysis for Amidomethylative Multiple Substitution Reactions of α-Substituted Styrene Derivatives. ACS Catalysis. 10 (18) 10627. https://pubs.acs.org/doi/10.1021/acscatal.0c02676
  • Peng, W., Athukorale, S., HU, J., Cui, X., Zhang, D. (2021). Kinetic spectroscopic quantification using two-step chromogenic and fluorogenic reactions: From theoretical modeling to experimental quantification of biomarkers in practical samples. Analytica Chimica Acta. 1153 (8) 338293. https://www.sciencedirect.com/science/article/pii/S0003267021001197?via%3Dihub
  • Riart-Ferrer, X., Sang, P., Tao, J., Xu, H., Jin, L., Lu, H., Cui, X., Wojtas, L., Zhang, X. (2021). Metalloradical activation of carbonyl azides for enantioselective radical aziridination. 7 (4) 1120. https://www.sciencedirect.com/science/article/pii/S2451929421001121?via%3Dihub
  • Zhang, X., Qiu, X., Rong, J., Su, S., Cui, X., Tao, C. (2019). Aryldiazonium ion initiated C–N bond cleavage for the versatile, efficient and regioselective ring opening of aziridines. 2019 (6) 1832. https://pubs.rsc.org/en/content/articlelanding/2019/qo/c9qo00320g
  • Li, Z., Chaminda Lakmal, H., Cui, X. (2019). Enabling Catalytic Arene C–H Amidomethylation via Bis(tosylamido)methane as a Sustainable Formaldimine Releaser. Organic Letters. 21 (10) 3735.
  • Hu, Y., Lang, K., Li, C., Gill, J., Kim, I., Lu, H., Fields, K., Marshall, M., Cheng, Q., Cui, X., Wojtas, L., Zhang, X. (2019). Enantioselective Radical Construction of 5-Membered Cyclic Sulfonamides by Metalloradical C–H Amination. Journal of the American Chemical Society. 141 (45) 18160.
  • Hu, Y., Lang, K., Tao, J., Marshall, M., Cheng, Q., Cui, X., Wojtas, L., Zhang, X. (2019). Next-Generation D2-Symmetric Chiral Porphyrins for Cobalt(II)-Based Metalloradical Catalysis: Catalyst Engineering by Distal Bridging. Angewandte Chemie International Edition. 58 (9) 2670. https://onlinelibrary.wiley.com/doi/10.1002/anie.201812379
  • Li, Z., Chaminda Lakmal, H., Qian, X., Zhu, Z., Donnadieu, B., McClain, S., Xu, X., Cui, X. (2019). Ruthenium-Catalyzed Enantioselective C–H Functionalization: A Practical Access to Optically Active Indoline Derivatives. Journal of the American Chemical Society. 141 (40) 15730. https://pubs.acs.org/doi/10.1021/jacs.9b07251
  • Li, C., Lang, K., Lu, H., Hu, Y., Cui, X., Wojtas, L., Zhang, X. (2018). Catalytic Radical Process for Enantioselective Amination of C(sp3)−H Bonds. Angewandte Chemie International Edition. 57 (51) 16837. https://onlinelibrary.wiley.com/doi/10.1002/anie.201808923
  • Wang, Y., Wen, X., Cui, X., Zhang, X. (2018). Enantioselective Radical Cyclization for Construction of 5-Membered Ring Structures by Metalloradical C–H Alkylation. Journal of the American Chemical Society. 140 (14) 4792. https://pubs.acs.org/doi/10.1021/jacs.8b01662
  • Chaminda Lakmal, H., Xu, J., Xu, X., Ahmed, B., Fong, C., Szalda, D., Ramig, K., Sygula, A., Webster, C., Zhang, D., Cui, X. (2018). Synthesis of C-Unsubstituted 1,2-Diazetidines and Their Ring-Opening Reactions via Selective N–N Bond Cleavage. Journal of Organic Chemistry. 83 (16) 9497. https://pubs.acs.org/doi/10.1021/acs.joc.8b01223
  • Wang, Y., Wen, X., Cui, X., Wojtas, L., Zhang, X. (2017). Asymmetric Radical Cyclopropanation of Alkenes with In Situ-Generated Donor-Substituted Diazo Reagents via Co(II)-Based Metalloradical Catalysis. Journal of the American Chemical Society. 139 (3) 1049. https://pubs.acs.org/doi/10.1021/jacs.6b11336
  • Zhou, H., Chaminda Lakmal, H., Baine, J., Valle, H., Xu, X., Cui, X. (2017). Catalytic [2 + 2 + 2] cycloaddition with indium(iii)-activated formaldimines: a practical and selective access to hexahydropyrimidines and 1,3-diamines from alkenes. Chemical Science. 2017 (8) 6520. https://pubs.rsc.org/en/content/articlelanding/2017/sc/c7sc02576a
  • Xu, X., Wang, Y., Cui, X., Wojtas, L., Zhang, X. (2017). Metalloradical activation of α-formyldiazoacetates for the catalytic asymmetric radical cyclopropanation of alkenes. Chemical Science. 2017 (8) 4347. https://pubs.rsc.org/en/content/articlelanding/2017/sc/c7sc00658f
  • Goswami, M., Lyaskovskyy, V., Domingos, S., Jan Buma, W., Woutersen, S., Troeppner, O., Ivanović-Burmazović, I., Lu, H., Cui, X., Zhang, X., Reijerse, E., DeBeer, S., van Schooneveld, M., Felix Pfaff, F., Ray, K., de Bruin, B. (2015). Characterization of Porphyrin-Co(III)-‘Nitrene Radical’ Species Relevant in Catalytic Nitrene Transfer Reactions. Journal of the American Chemical Society. 137 (16) 5468. https://pubs.acs.org/doi/10.1021/jacs.5b01197
  • Subbarayan, V., Jin, L., Cui, X., Zhang, X. (2015). Room temperature activation of aryloxysulfonyl azides by [Co(II)(TPP)] for selective radical aziridination of alkenes via metalloradical catalysis. Tetrahedron. 56 (23) 3431. https://www.sciencedirect.com/science/article/pii/S0040403915002361?via%3Dihub
  • Cui, X., Xu, X., Jin, L., Wojtas, L., Zhang, X. (2015). Stereoselective radical C–H alkylation with acceptor/acceptor-substituted diazo reagents via Co(ii)-based metalloradical catalysis. Chemical Science. 2015 (6) 1219. https://pubs.rsc.org/en/content/articlelanding/2015/sc/c4sc02610a
  • Paul, N., Mandal, S., Otte, M., Cui, X., Zhang, X., de Bruin, B. (2014). Metalloradical Approach to 2H-Chromenes. Journal of the American Chemical Society. 136 (3) 1090. https://pubs.acs.org/doi/10.1021/ja4111336
  • Jin, L., Lu, H., Lizardi, C., Arzua, T., Wojtas, L., Cui, X., Zhang, X. (2014). Selective radical amination of aldehydic C(sp2)–H bonds with fluoroaryl azides via Co(ii)-based metalloradical catalysis: synthesis of N-fluoroaryl amides from aldehydes under neutral and nonoxidative conditions. Chemical Science. (5) 2422.

Contracts, Grants and Sponsored Research

    Grant - Research

  • Cui, X., "CAREER: Ruthenium-Catalyzed Stereoselective and Site-selective Functionalization of Carbon-Hydrogen Bond," sponsored by NSF, Federal, $650000 Funded. (2020 - 2025).
  • Cui, X., "NSF Supplemental Funding for NSF-ERC Research Collaboration," sponsored by NSF, Federal, $11921 Funded. (2023 - 2024).
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Overall
Summative Rating
Challenge and
Engagement Index
Response Rate

out of 5

out of 7
%
of
students responded
  • Overall Summative Rating (median):
    This rating represents the combined responses of students to the four global summative items and is presented to provide an overall index of the class’s quality. Overall summative statements include the following (response options include a Likert scale ranging from 5 = Excellent, 3 = Good, and 1= Very poor):
    • The course as a whole was
    • The course content was
    • The instructor’s contribution to the course was
    • The instructor’s effectiveness in teaching the subject matter was
  • Challenge and Engagement Index:
    This rating combines student responses to several SPOT items relating to how academically challenging students found the course to be and how engaged they were. Challenge and Engagement Index items include the following (response options include a Likert scale ranging from 7 = Much higher, 4 = Average, and 1 = Much lower):
    • Do you expect your grade in this course to be
    • The intellectual challenge presented was
    • The amount of effort you put into this course was
    • The amount of effort to succeed in this course was
    • Your involvement in course (doing assignments, attending classes, etc.) was
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