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Yanxiao Han

Title: Assistant Professor

Department: Biological Sciences

College: College of Science

Curriculum Vitae

Curriculum Vitae Link

Current Scheduled Teaching

BIOL 4005.008Contemporary Topics in BiologySpring 2026 Syllabus
BIOL 5005.008TOPICS IN BIOLOGYSpring 2026
Texas Education Code 51.974 (HB 2504) requires each institution of higher education to make available to the public, a syllabus for undergraduate lecture courses offered for credit by the institution.

Previous Scheduled Teaching

No previous courses scheduled.

Texas Education Code 51.974 (HB 2504) requires each institution of higher education to make available to the public, a syllabus for undergraduate lecture courses offered for credit by the institution.

Published Intellectual Contributions

    Abstracts and Proceedings

  • Han, Y., Rouen, K., Xiang, Y.K., Yarov-Yarovoy, V., Clancy, C.E., Ahn, S., Vorobyov, I.V. (2025). BPS2025-In silico pipeline to assess the dynamic interplay between $\beta$-adrenergic receptors, its agonists, and different G proteins. Biophysical Journal. 124 (3) 234a. Elsevier.
  • Ngo, K., Mateos, D.L., Han, Y., Rouen, K.C., Ahn, S., Wulff, H., Clancy, C.E., Yarov-Yarovoy, V., Vorobyov, I. (2024). From Tarantula Venom to Therapeutics: Unveiling Protoxin-2’s Binding to Pain-Sensing Human NaV1. 7 Channels. Other. 67.

    • Book Chapter

  • DeMarco, K.R., Dawson, J.R., Rouen, K.C., Ngo, K., Han, Y., Yang, P., Bekker, S., Ngo, Van A, Noskov, S.Y., Yarov-Yarovoy, V., others. (2025). Atomistic Modeling Toward Predictive Cardiotoxicity. Molecular and Computational Modeling of Cardiac Function. 77--118. Springer.
  • Bekker, S., Han, Y., Vorobyov, I. (2025). Introduction to Atomistic Modeling and Simulation of Biomolecular Systems. Molecular and Computational Modeling of Cardiac Function. 1--75. Springer.

    • Journal Article

  • Rouen, K.C., Narang, K., Han, Y., Wang, D., Jang, E., Brunkow, S., Yarov-Yarovoy, V., MacKerell, Jr, A.D., Vorobyov, I. (2025). Arrhythmia risk predictions from molecular simulations of cardiac ion channel-drug interactions. Biophysical Journal. 2025--09. Cell Press.
  • Han, Y., Rouen, K.C., Yarov-Yarovoy, V., Clancy, C.E., Xiang, Y.K., Vorobyov, I., Ahn, S. (2025). Ligand Dissociation Pathways from Membrane Receptors Revealed by Weighted Ensemble Simulations. The Journal of Physical Chemistry B. ACS Publications.
  • Han, Y., Dawson, J.R., DeMarco, K.R., Rouen, K.C., Ngo, K., Bekker, S., Yarov-Yarovoy, V., Clancy, C.E., Xiang, Y.K., Ahn, S., others. (2025). Molecular simulations reveal intricate coupling between agonist-bound $\beta$-Adrenergic Receptors and G Protein. iScience. 111741. Elsevier.
  • Yang, P., Rose, A., DeMarco, K.R., Dawson, J.R., Han, Y., Jeng, M., Harvey, R.D., Santana, L.F., Ripplinger, C.M., Vorobyov, I., others. (2023). A multiscale predictive digital twin for neurocardiac modulation. Journal of Physiology. 601 (17) 3789--3812.
  • Han, Y., Dawson, J.R., DeMarco, K.R., Rouen, K.C., Bekker, S., Yarov-Yarovoy, V., Clancy, C.E., Xiang, Y.K., Vorobyov, I. (2023). Elucidation of a dynamic interplay between a beta-2 adrenergic receptor, its agonist, and stimulatory G protein. Proceedings of the National Academy of Sciences. 120 (10) e2215916120. National Acad Sciences.
  • Kr\'al, Petr, Chan, H., Vukovi\'c, Lela, Raj, S., Sen, S., Han, Y., Sawczyk, M. (2023). Simulation Methods for Self-Assembling Nanoparticles. Other. 101225. Elsevier.

    • Manuscript

  • Dawson, J.R., DeMarco, K.R., Han, Y., Bekker, S., Clancy, C.E., Yarov-Yarovoy, V., Vorobyov, I. (2023). Modeling stereospecific drug interactions with beta-adrenergic receptors. Other. 2023--10. Cold Spring Harbor Laboratory.

Contracts, Grants and Sponsored Research

    Grant - Research

  • Han, Y. (Principal), "Pharmacological Modulation of Estrogen and Adrenergic Receptors," sponsored by American Heart Association, National, $231000 Funded. (2025 - 2028).
  • Han, Y. (Principal), "Cooperation of Estrogen and Adrenergic Receptors in Cardiovascular Function: Mechanism and Impact," sponsored by American Heart Association, National, $151564 Funded. (2024 - 2025).
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Overall
Summative Rating		 Challenge and
Engagement Index		 Response Rate

out of 5
out of 7		 %
of
students responded
  • Overall Summative Rating (median):
    This rating represents the combined responses of students to the four global summative items and is presented to provide an overall index of the class’s quality. Overall summative statements include the following (response options include a Likert scale ranging from 5 = Excellent, 3 = Good, and 1= Very poor):
    • The course as a whole was
    • The course content was
    • The instructor’s contribution to the course was
    • The instructor’s effectiveness in teaching the subject matter was
  • Challenge and Engagement Index:
    This rating combines student responses to several SPOT items relating to how academically challenging students found the course to be and how engaged they were. Challenge and Engagement Index items include the following (response options include a Likert scale ranging from 7 = Much higher, 4 = Average, and 1 = Much lower):
    • Do you expect your grade in this course to be
    • The intellectual challenge presented was
    • The amount of effort you put into this course was
    • The amount of effort to succeed in this course was
    • Your involvement in course (doing assignments, attending classes, etc.) was
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